Efficacy of a pit and fissure sealant in arresting dentin non-cavitated caries: a 1-year follow-up, randomized, single-blind, controlled clinical trial.

PURPOSE: To evaluate the efficacy of conservative treatment of dentin non-cavitated caries using a resin-based fluoride-containing pit and fissure sealant.
METHODS: In this controlled clinical trial, 60 teeth with clinically non-cavitated occlusal caries radiographically located beneath the enamel-dentin junction (radiolucent area) were selected among patients presenting a moderate to high caries risk. The teeth were randomly divided into two groups of 30 teeth each: an experimental group receiving an application of Fluorshield (Dentsply) sealant and a control group not submitted to any clinical intervention. Caries progression was monitored by clinical and radiographic examination at 4-month intervals over a period of 1 year. In addition, marginal integrity of the sealant was evaluated in the experimental group.
RESULTS: Clinical and radiographic caries progression was significantly more frequent in control teeth when compared to the experimental group (P < 0.05).

RCT Entities:   Population Interventions Outcomes