Osteomyelitis of skull with underlying brain abscess.

Neonatal osteomyelitis of the calvaria is a rare condition. The present case report describes a 4-week-old infant with osteomyelitis of the right parietal and temporal bones caused by Staphylococcus aureus. CT scan revealed a characteristic "moth-eaten" appearance and multiloculated brain abscess with encephalomalacia, which was successfully treated by appropriate intravenous antibiotics along with surgical drainage . In follow up, baby developed spastic cerebral palsy of hemiplegic type.