Literature DB >> 21342254

Fulminant hepatitis and glomerulonephritis--a rare presentation of hepatitis A virus infection.

Radha B Pal1, Pritam Saha, Ira Das, Malay K Sinha.   

Abstract

AIM: We report a case of fulminant hepatitis and glomerulonephritis by Hepatitis A virus infection.
METHODS: We observed the patient's clinical course and analyzed his data retrospectively.
RESULTS: The three-year-old boy presented with features of acute renal failure and stage 2 hepatic encephalopathy. Renal biopsy showed diffuse mesangioproliferative glomerulonephritis with immunoglobulin M and complement 3 deposition. After receiving supportive treatment for over 6 weeks, the hepatic and renal function became normal. Renal biopsy after 3 months was normal.
CONCLUSION: Acute renal failure is a rare complication of Hepatitis A virus infection. Physicians should be aware of the potential renal involvement of Hepatitis A virus infection as the prognosis is not always favourable.
© 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.

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Year:  2011        PMID: 21342254     DOI: 10.1111/j.1651-2227.2011.02231.x

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


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