Literature DB >> 21340054

Hypervalent phenyl-λ3-iodane-mediated para-selective aromatic fluorination of 3-phenylpropyl ethers.

Motomichi Saito1, Kazunori Miyamoto, Masahito Ochiai.   

Abstract

Exposure of 3-phenylpropyl ethers to an activated iodosylbenzene monomer·18-crown-6 complex [PhI(OH)BF(4)·18C6] in the presence of BF(3)-Et(2)O and water results in the para-selective monofluorination of benzene ring via neighboring alkoxy group participation and directly affords 3-(4-fluorophenyl)propyl ethers regioselectively in good yields.

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Year:  2011        PMID: 21340054     DOI: 10.1039/c1cc10215j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  A Novel Synthesis of 4-Acetoxyl 5(4H)-Oxazolones by Direct α-Oxidation of N-Benzoyl Amino-Acid Using Hypervalent Iodine.

Authors:  Gang Wen; Wen-Xuan Zhang; Song Wu
Journal:  Molecules       Date:  2017-07-03       Impact factor: 4.411

  1 in total

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