Literature DB >> 21338993

Acylphloroglucinol and xanthones from Hypericum ellipticum.

Kylie Manning1, Elyse Petrunak, Michelle Lebo, Antonio González-Sarrías, Navindra P Seeram, Geneive E Henry.   

Abstract

An acylphloroglucinol, elliptophenone A, and two xanthones, elliptoxanthone A and elliptoxanthone B, were isolated from the aerial portions of Hypericum ellipticum together with three known xanthones, 1,3,7-trihydroxy-8-(3-methyl-2-butenyl)-9H-xanthen-9-one, 1,6-dihydroxy-4-methoxy-9H-xanthen-9-one, and 1,4,5-trihydroxy-9H-xanthen-9-one. Their structures were determined by spectroscopic analyses. The acylphloroglucinol and xanthones were evaluated for cytotoxicity using three human colon cancer cell lines cell lines (HT-29, HCT-116 and Caco-2) and a normal human colon cell line (CCD-18Co).
Copyright © 2011 Elsevier Ltd. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2011        PMID: 21338993     DOI: 10.1016/j.phytochem.2011.01.032

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  2 in total

1.  Inhibition of bacterial growth and biofilm production by constituents from Hypericum spp.

Authors:  S A Sarkisian; M J Janssen; H Matta; G E Henry; K L Laplante; D C Rowley
Journal:  Phytother Res       Date:  2011-12-15       Impact factor: 5.878

2.  Identification and biosynthesis of acylphloroglucinols in Hypericum gentianoides.

Authors:  Matthew C Crispin; Manhoi Hur; Taeseong Park; Young Hwan Kim; Eve Syrkin Wurtele
Journal:  Physiol Plant       Date:  2013-05-24       Impact factor: 4.500

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.