| Literature DB >> 21338073 |
Wei-Hua Chen1, Yu Xing, Yi Pang.
Abstract
Pyrophosphate (PPi) is a biologically important target. A binuclear system 3•2Zn is found to selectively recognize PPi, leading to a ratiometric fluorescent sensor at pH 7.4 in water. The binding event triggered a large fluorescence response (∼100 nm bathochromic shift) by turning on the excited state intramolecular proton transfer (ESIPT). Detection of PPi released from a PCR experiment indicated that this new probe could be a useful tool in bioanalytical applications.Entities:
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Year: 2011 PMID: 21338073 DOI: 10.1021/ol200054w
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005