Literature DB >> 21336179

Pulmonary embolism diagnosed on computed tomography contrast angiography despite negative venous Doppler ultrasound after spinal surgery.

Nancy E Epstein1, Harry Staszewski, Michael Garrison, Man Hon.   

Abstract

STUDY
DESIGN: The focus of this study was on the frequency of negative initial/subsequent ultrasound (US) of the lower extremities but positive spinal computed tomography contrast angiography (CTA) diagnostic of pulmonary embolism (PE) among 75 patients undergoing cervical laminectomy/fusion and 165 patients having lumbar laminectomy/noninstrumented fusion.
OBJECTIVE: To determine the percentage/incidence of patients undergoing spinal surgery with negative US but with positive CTA. SUMMARY OF BACKGROUND DATA: The frequency of patients with negative US but with positive CTA after spinal surgery is not well documented.
METHODS: For 240 spinal surgery patients, postoperative prophylaxis against deep venous thrombosis consisted of alternating pneumatic compression stockings alone. The patients were routinely screened on postoperative days 1 to 2 for deep venous thrombosis using US. The incidence of initial/subsequent negative US and positive CTA diagnostic for PE in patients with mild/major symptoms was evaluated, in conjunction with the frequency of hypercoagulation syndromes.
RESULTS: Five (6.7%) patients undergoing cervical surgery and 6 patients (3.6%) undergoing lumbar surgery exhibited negative US but positive CTA on postoperative days 1 to 21. All the patients immediately received inferior vena cava filters (2 permanent and 9 retrievable). Five patients (45%) tested positive for hypercoagulation syndromes. Two patients were fully anticoagulated on postoperative days 3 and 21 with major symptoms attributed to saddle emboli; 1 had hypercoagulation syndrome. Anticoagulation was delayed for 6 to 12 weeks in 7 patients with milder symptoms, as magnetic resonance imaging scans showed residual seromas; 4 had hypercoagulation syndromes. Two elderly patients, at high risk for falls, without hypercoagulation syndromes were not anticoagulated.
CONCLUSIONS: The frequency of negative US of the lower extremities but with positive CTA for PE after 240 cervical/lumbar spinal procedures in patients with mild/major symptoms ranged from 3.6% to 6.7%; 5 of the 11 patients exhibited hypercoagulation syndromes. To avoid failure to diagnose PE after spinal surgery, one should have a "low threshold" (eg, based even on minor symptoms) for requesting the CTA.

Entities:  

Mesh:

Year:  2011        PMID: 21336179     DOI: 10.1097/BSD.0b013e3181fee66a

Source DB:  PubMed          Journal:  J Spinal Disord Tech        ISSN: 1536-0652


  4 in total

1.  Incidental pulmonary embolism in suspected stroke patients undergoing carotid CT angiography.

Authors:  Guang-Liang Chen; Dong-Hui Shen; Jin Wei; Hua Wang; Yuan-Fen Liu; Qing Duan
Journal:  Radiol Med       Date:  2018-02-09       Impact factor: 3.469

2.  24-48 hour preoperative "surveillance" lower extremity venous Doppler's: Aren't they worthwhile prior to spine surgery?

Authors:  Nancy E Epstein
Journal:  Surg Neurol Int       Date:  2016-12-26

3.  How much medicine do spine surgeons need to know to better select and care for patients?

Authors:  Nancy E Epstein
Journal:  Surg Neurol Int       Date:  2012-11-26

4.  Venous Thromboembolism Prophylaxis in Elective Spine Surgery.

Authors:  Samantha Solaru; Ram K Alluri; Jeffrey C Wang; Raymond J Hah
Journal:  Global Spine J       Date:  2020-10-09
  4 in total

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