Literature DB >> 21335457

Crystal structure of the autochaperone region from the Shigella flexneri autotransporter IcsA.

Karin Kühnel1, Dagmar Diezmann.   

Abstract

The IcsA (intracellular spread gene A) autotransporter from Shigella flexneri is a key virulence factor. We identified a stable fragment comprising residues 591 to 758, which corresponds to the autochaperone region of the IcsA passenger domain. We showed that thermal unfolding of the autochaperone region is reversible and determined its crystal structure at 2.0-Å resolution.

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Year:  2011        PMID： 21335457      PMCID： PMC3133035          DOI： 10.1128/JB.00790-10

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  30 in total

1.  Escape of intracellular Shigella from autophagy.

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Journal:  Science       Date:  2004-12-02       Impact factor: 47.728

Review 2.  How to study proteins by circular dichroism.

Authors:  Sharon M Kelly; Thomas J Jess; Nicholas C Price
Journal:  Biochim Biophys Acta       Date:  2005-08-10

3.  Pertactin beta-helix folding mechanism suggests common themes for the secretion and folding of autotransporter proteins.

Authors:  Mirco Junker; Christopher C Schuster; Andrew V McDonnell; Kelli A Sorg; Mary C Finn; Bonnie Berger; Patricia L Clark
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-20       Impact factor: 11.205

4.  Vectorial transport and folding of an autotransporter virulence protein during outer membrane secretion.

Authors:  Mirco Junker; Richard N Besingi; Patricia L Clark
Journal:  Mol Microbiol       Date:  2009-01-26       Impact factor: 3.501

5.  Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri.

Authors:  T Suzuki; H Miki; T Takenawa; C Sasakawa
Journal:  EMBO J       Date:  1998-05-15       Impact factor: 11.598

6.  Crystal structure of hemoglobin protease, a heme binding autotransporter protein from pathogenic Escherichia coli.

Authors:  Ben R Otto; Robert Sijbrandi; Joen Luirink; Bauke Oudega; Jonathan G Heddle; Kenji Mizutani; Sam-Yong Park; Jeremy R H Tame
Journal:  J Biol Chem       Date:  2005-02-22       Impact factor: 5.157

7.  Mutagenesis of the Shigella flexneri autotransporter IcsA reveals novel functional regions involved in IcsA biogenesis and recruitment of host neural Wiscott-Aldrich syndrome protein.

Authors:  Kerrie L May; Renato Morona
Journal:  J Bacteriol       Date:  2008-05-02       Impact factor: 3.490

8.  Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain.

Authors:  Kelly A Gangwer; Darren J Mushrush; Devin L Stauff; Ben Spiller; Mark S McClain; Timothy L Cover; D Borden Lacy
Journal:  Proc Natl Acad Sci U S A       Date:  2007-10-02       Impact factor: 11.205

9.  Developments in the CCP4 molecular-graphics project.

Authors:  Liz Potterton; Stuart McNicholas; Eugene Krissinel; Jan Gruber; Kevin Cowtan; Paul Emsley; Garib N Murshudov; Serge Cohen; Anastassis Perrakis; Martin Noble
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2004-11-26

10.  A conserved stable core structure in the passenger domain beta-helix of autotransporter virulence proteins.

Authors:  Jonathan P Renn; Patricia L Clark
Journal:  Biopolymers       Date:  2008-05       Impact factor: 2.505
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  12 in total

Review 1.  Shigella: a model of virulence regulation in vivo.

Authors:  Benoit Marteyn; Anastasia Gazi; Philippe Sansonetti
Journal:  Gut Microbes       Date:  2012-03-01

2.  The inverse autotransporter intimin exports its passenger domain via a hairpin intermediate.

Authors:  Philipp Oberhettinger; Jack C Leo; Dirk Linke; Ingo B Autenrieth; Monika S Schütz
Journal:  J Biol Chem       Date:  2014-12-08       Impact factor: 5.157

Review 3.  Of linkers and autochaperones: an unambiguous nomenclature to identify common and uncommon themes for autotransporter secretion.

Authors:  Igor Drobnak; Esther Braselmann; Julie L Chaney; Denisse L Leyton; Harris D Bernstein; Trevor Lithgow; Joen Luirink; James P Nataro; Patricia L Clark
Journal:  Mol Microbiol       Date:  2014-11-24       Impact factor: 3.501

4.  Crystal structure of the passenger domain of the Escherichia coli autotransporter EspP.

Authors:  Shekeb Khan; Hira S Mian; Linda E Sandercock; Nickolay Y Chirgadze; Emil F Pai
Journal:  J Mol Biol       Date:  2011-09-22       Impact factor: 5.469

5.  The Shigella Virulence Factor IcsA Relieves N-WASP Autoinhibition by Displacing the Verprolin Homology/Cofilin/Acidic (VCA) Domain.

Authors:  Rui P M Mauricio; Cy M Jeffries; Dmitri I Svergun; Janet E Deane
Journal:  J Biol Chem       Date:  2016-11-23       Impact factor: 5.157

6.  Effect of Adiantum philippense Extract on Biofilm Formation, Adhesion With Its Antibacterial Activities Against Foodborne Pathogens, and Characterization of Bioactive Metabolites: An in vitro-in silico Approach.

Authors:  Mohd Adnan; Mitesh Patel; Sumukh Deshpande; Mousa Alreshidi; Arif Jamal Siddiqui; Mandadi Narsimha Reddy; Noumi Emira; Vincenzo De Feo
Journal:  Front Microbiol       Date:  2020-05-13       Impact factor: 5.640

7.  The virulence domain of Shigella IcsA contains a subregion with specific host cell adhesion function.

Authors:  Jilong Qin; Matthew Thomas Doyle; Elizabeth Ngoc Hoa Tran; Renato Morona
Journal:  PLoS One       Date:  2020-01-07       Impact factor: 3.240

8.  Identification of Shigella flexneri IcsA residues affecting interaction with N-WASP, and evidence for IcsA-IcsA co-operative interaction.

Authors:  Min Yan Teh; Renato Morona
Journal:  PLoS One       Date:  2013-02-06       Impact factor: 3.240

9.  Identification of the Autochaperone Domain in the Type Va Secretion System (T5aSS): Prevalent Feature of Autotransporters with a β-Helical Passenger.

Authors:  Maricarmen Rojas-Lopez; Mohamed A Zorgani; Lawrence A Kelley; Xavier Bailly; Andrey V Kajava; Ian R Henderson; Fabio Polticelli; Mariagrazia Pizza; Roberto Rosini; Mickaël Desvaux
Journal:  Front Microbiol       Date:  2018-01-05       Impact factor: 5.640

10.  Cardiolipin Synthesis and Outer Membrane Localization Are Required for Shigella flexneri Virulence.

Authors:  Rachael M Rossi; Lauren Yum; Hervé Agaisse; Shelley M Payne
Journal:  mBio       Date:  2017-08-29       Impact factor: 7.867
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