Literature DB >> 21334948

Paradoxical exacerbation of tuberculosis after TNFα antagonist discontinuation: beware of immune reconstitution inflammatory syndrome.

Claire Rivoisy1, Lucile Amrouche, Guislaine Carcelain, Daniel Séréni, Anne Bourgarit.   

Abstract

Paradoxical worsening of tuberculosis associated with immune reconstitution during antiretroviral therapy in patients with HIV infection is known as the immune reconstitution inflammatory syndrome (IRIS). Here, we report a case of paradoxical worsening of IFN-alpha induced tuberculosis in a patient experiencing reconstitution of pathogen-specific immune responses after discontinuing TNFα antagonist therapy. This case serves to alert clinicians that complications such as tuberculosis may worsen after TNFα antagonist discontinuation. This situation may paradoxically require readministration of the immunosuppressive drug in some patients.
Copyright © 2011 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved.

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Year:  2011        PMID: 21334948     DOI: 10.1016/j.jbspin.2011.01.003

Source DB:  PubMed          Journal:  Joint Bone Spine        ISSN: 1297-319X            Impact factor:   4.929


  7 in total

1.  Tuberculosis of the breast: an uncommon presentation of an old disease.

Authors:  Maria Antonia Galego; Gisela Lage; Maria Shekhovtsova; Raquel Duarte
Journal:  BMJ Case Rep       Date:  2019-02-22

Review 2.  Immune reconstitution inflammatory syndrome: the trouble with immunity when you had none.

Authors:  Daniel L Barber; Bruno B Andrade; Irini Sereti; Alan Sher
Journal:  Nat Rev Microbiol       Date:  2012-01-09       Impact factor: 60.633

3.  Robust Reconstitution of Tuberculosis-Specific Polyfunctional CD4+ T-Cell Responses and Rising Systemic Interleukin 6 in Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome.

Authors:  Shruthi Ravimohan; Neo Tamuhla; Kebatshabile Nfanyana; Andrew P Steenhoff; Rona Letlhogile; Ian Frank; Rob Roy MacGregor; Robert Gross; Drew Weissman; Gregory P Bisson
Journal:  Clin Infect Dis       Date:  2015-11-26       Impact factor: 9.079

4.  Paradoxical reactions during treatment of tuberculosis with extrapulmonary manifestations in HIV-negative patients.

Authors:  G Geri; A Passeron; B Heym; J-B Arlet; J Pouchot; L Capron; B Ranque
Journal:  Infection       Date:  2012-12-01       Impact factor: 3.553

Review 5.  Immune reconstitution inflammatory syndrome associated with biologic therapy.

Authors:  Malika Gupta; Kashif Jafri; Rebecca Sharim; Susanna Silverman; Sayantani B Sindher; Anupama Shahane; Mildred Kwan
Journal:  Curr Allergy Asthma Rep       Date:  2015-02       Impact factor: 4.919

6.  Pathology in euthermic bats with white nose syndrome suggests a natural manifestation of immune reconstitution inflammatory syndrome.

Authors:  Carol U Meteyer; Daniel Barber; Judith N Mandl
Journal:  Virulence       Date:  2012-11-15       Impact factor: 5.882

Review 7.  Use of steroids to treat anti-tumor necrosis factor α induced tuberculosis-associated immune reconstitution inflammatory syndrome: Case report and literature review.

Authors:  Daijiro Nabeya; Takeshi Kinjo; Kazutaka Yamaniha; Shoshin Yamazato; Reo Tome; Kazuya Miyagi; Hideta Nakamura; Tetsu Kinjo; Shusaku Haranaga; Futoshi Higa; Jiro Fujita
Journal:  Medicine (Baltimore)       Date:  2020-10-23       Impact factor: 1.817

  7 in total

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