Literature DB >> 21334092

Bronchoalveolar lavage fluid of lung cancer patients: mapping the uncharted waters using proteomics technology.

Tonio Oumeraci, Bernd Schmidt, Thomas Wolf, Marc Zapatka, Andreas Pich, Benedikt Brors, Roland Eils, Michael Fleischhacker, Brigitte Schlegelberger, Nils von Neuhoff.   

Abstract

The search for proteome-level markers of non-small cell lung cancer (NSCLC) has been mainly limited to serum or cell line screening approaches up to this point. We would like to demonstrate by this proof-of-principle study investigating bronchoalveolar lavage fluid samples from a cohort of NSCLC and control patients, that this readily available biofluid might be a more suitable source for discovering clinically usable NSCLC biomarkers.
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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Year:  2011        PMID: 21334092     DOI: 10.1016/j.lungcan.2011.01.015

Source DB:  PubMed          Journal:  Lung Cancer        ISSN: 0169-5002            Impact factor:   5.705


  6 in total

1.  Glycoproteomic analysis of bronchoalveolar lavage (BAL) fluid identifies tumor-associated glycoproteins from lung adenocarcinoma.

Authors:  Qing Kay Li; Punit Shah; Yan Li; Paul O Aiyetan; Jing Chen; Rex Yung; Daniela Molena; Edward Gabrielson; Frederic Askin; Daniel W Chan; Hui Zhang
Journal:  J Proteome Res       Date:  2013-07-11       Impact factor: 4.466

2.  Application of proteomics to cancer early detection.

Authors:  Samir Hanash; Ayumu Taguchi
Journal:  Cancer J       Date:  2011 Nov-Dec       Impact factor: 3.360

3.  Characterization of the phosphoproteome in human bronchoalveolar lavage fluid.

Authors:  Francesco Giorgianni; Valentina Mileo; Dominic M Desiderio; Silvia Catinella; Sarka Beranova-Giorgianni
Journal:  Int J Proteomics       Date:  2012-09-11

4.  Quantum-dot-based suspension microarray for multiplex detection of lung cancer markers: preclinical validation and comparison with the Luminex xMAP® system.

Authors:  Regina Bilan; Amagoia Ametzazurra; Kristina Brazhnik; Sergio Escorza; David Fernández; María Uríbarri; Igor Nabiev; Alyona Sukhanova
Journal:  Sci Rep       Date:  2017-03-16       Impact factor: 4.379

5.  Bronchoalveolar Lavage Proteomics in Patients with Suspected Lung Cancer.

Authors:  Ana Sofia Carvalho; Célia Marina Cuco; Carla Lavareda; Francisco Miguel; Mafalda Ventura; Sónia Almeida; Paula Pinto; Tiago Tavares de Abreu; Luís Vaz Rodrigues; Susana Seixas; Cristina Bárbara; Mikel Azkargorta; Felix Elortza; Júlio Semedo; John K Field; Leonor Mota; Rune Matthiesen
Journal:  Sci Rep       Date:  2017-02-07       Impact factor: 4.379

6.  Compared to plasma, bronchial washing fluid shows higher diagnostic yields for detecting EGFR-TKI sensitizing mutations by ddPCR in lung cancer.

Authors:  Sang Hoon Lee; Eun Young Kim; Taehee Kim; Yoon Soo Chang
Journal:  Respir Res       Date:  2020-06-09
  6 in total

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