Literature DB >> 21333937

Transoral robotic photodynamic therapy for the oropharynx.

Harry Quon1, Jarod Finlay, Keith Cengel, Timothy Zhu, Bert O'Malley, Gregory Weinstein.   

Abstract

Photodynamic therapy (PDT) has been used for head and neck carcinomas with little experience in the oropharynx due to technical challenges in achieving adequate exposure. We present the case of a patient with a second right tonsil carcinoma following previous treatment with transoral robotic surgery (TORS) and postoperative chemoradiation for a left tonsil carcinoma. Repeat TORS for the right tonsil carcinoma reviewed multiple positive surgical margins. The power output from the robotic camera was modified to facilitate safe intraoperative three dimensional visualization of the tumor bed. The robotic arms facilitated clear exposure of the tonsil and tongue base with stable administration of the fluence. Real-time measurements confirmed stable photobleaching with augmentation of the prescribed light fluence secondary to light scatter in the oropharynx. We report a potential new role using TORS for exposure and accurate PDT in the oropharynx.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID: 21333937      PMCID: PMC4394013          DOI: 10.1016/j.pdpdt.2010.12.005

Source DB:  PubMed          Journal:  Photodiagnosis Photodyn Ther        ISSN: 1572-1000            Impact factor:   3.631


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  3 in total

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