Literature DB >> 21333676

Sat-Nav for T cells: Role of PI3K isoforms and lipid phosphatases in migration of T lymphocytes.

Stephen G Ward1, John Westwick, Stephanie Harris.   

Abstract

Phosphoinositide 3-kinase (PI3K)-dependent signaling has been placed at the heart of conserved biochemical mechanisms that facilitate cell migration of leukocytes in response to a range of chemoattractant stimuli. This review assesses the evidence for and against PI3K-dependent mechanisms of T lymphocyte migration and whether pharmacological targeting of PI3K isoforms is likely to offer potential benefit for T cell mediated pathologies.
Copyright © 2011 Elsevier B.V. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21333676     DOI： 10.1016/j.imlet.2011.02.007

Source DB:  PubMed          Journal:  Immunol Lett        ISSN： 0165-2478            Impact factor:   3.685


  6 in total

1.  Inhibition of TGF-β2-induced migration and epithelial-mesenchymal transition in ARPE-19 by sulforaphane.

Authors:  Yan-Bing Huang; Ping-Ping Liu; Hui Zheng; Xiu-Xia Yang; Cheng-Cheng Yang; Ye Liu; Yang Liu
Journal:  Int J Ophthalmol       Date:  2021-07-18       Impact factor: 1.779

2.  Glioma cells promote the expression of vascular cell adhesion molecule-1 on bone marrow-derived mesenchymal stem cells: a possible mechanism for their tropism toward gliomas.

Authors:  Yi Hu; Peng Cheng; Yi-Xue Xue; Yun-Hui Liu
Journal:  J Mol Neurosci       Date:  2012-05-06       Impact factor: 3.444

3.  Determinants of phosphatidylinositol-4-phosphate 5-kinase type Iγ90 uropod location in T-lymphocytes and its role in uropod formation.

Authors:  Lucia Mathis; Sarah Wernimont; Sarah Affentranger; Anna Huttenlocher; Verena Niggli
Journal:  PeerJ       Date:  2013-08-29       Impact factor: 2.984

4.  The Effect of Sanggua Drink Extract on Insulin Resistance through the PI3K/AKT Signaling Pathway.

Authors:  Yu Cai; Ying Wang; Fei Zhi; Qi-Chang Xing; Yun-Zhong Chen
Journal:  Evid Based Complement Alternat Med       Date:  2018-02-19       Impact factor: 2.629

5.  Synergistic Hypoglycemic Effects of Pumpkin Polysaccharides and Puerarin on Type II Diabetes Mellitus Mice.

Authors:  Xue Chen; Lei Qian; Bujiang Wang; Zhijun Zhang; Han Liu; Yeni Zhang; Jinfu Liu
Journal:  Molecules       Date:  2019-03-08       Impact factor: 4.411

6.  Accumulation of splice variants and transcripts in response to PI3K inhibition in T cells.

Authors:  Alice Riedel; Boitumelo Mofolo; Elita Avota; Sibylle Schneider-Schaulies; Ayton Meintjes; Nicola Mulder; Susanne Kneitz
Journal:  PLoS One       Date:  2013-02-01       Impact factor: 3.240
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.