Literature DB >> 21333534

Development of 2,4-diaminopyrimidine derivatives as novel SNSR4 antagonists.

Malken Bayrakdarian1, Joanne Butterworth, Yun-Jin Hu, Vijayaratnam Santhakumar, Mirosław J Tomaszewski.   

Abstract

2,4-Diaminopyrimidines derivatives were developed as a novel class of SNSR4 antagonists. Structure activity relationship of the diamino pyrimidine core was explored and a tool compound suitable for target validation was identified.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21333534     DOI: 10.1016/j.bmcl.2011.01.138

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors.

Authors:  Niyada Hin; Jesse Alt; Sarah C Zimmermann; Greg Delahanty; Dana V Ferraris; Camilo Rojas; Fengxian Li; Qin Liu; Xinzhong Dong; Barbara S Slusher; Takashi Tsukamoto
Journal:  Bioorg Med Chem       Date:  2014-09-19       Impact factor: 3.641

2.  Antiproliferative Activity of (-)-Isopulegol-based 1,3-Oxazine, 1,3-Thiazine and 2,4-Diaminopyrimidine Derivatives.

Authors:  Fatima Z Bamou; Tam M Le; Bizhar A Tayeb; Seyyed A S Tahaei; Renáta Minorics; István Zupkó; Zsolt Szakonyi
Journal:  ChemistryOpen       Date:  2022-10       Impact factor: 2.630

  2 in total

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