Literature DB >> 21332609

The accuracy of using integrated electronic health care data to identify patients with undiagnosed diabetes mellitus.

Michael L Ho1, Nadine Lawrence, Carl van Walraven, Doug Manuel, Erin Keely, Janine Malcolm, Robert D Reid, Alan J Forster.   

Abstract

RATIONALE, AIMS AND
OBJECTIVES: Diabetes mellitus is a growing health and economic burden. Identification of patients with unrecognized diabetes, or those at high risk for diabetes, provides an opportunity for timely intervention. This study assessed the accuracy of using electronic health care data to identify patients with undiagnosed diabetes.
METHODS: The study was conducted at a tertiary-care teaching facility in Ottawa, Canada. The study cohort was a stratified random sample of hospitalizations between 1 January 2003 and 31 December 2008. We used diagnostic codes, pharmacy orders and serum glucose tests to classify patients into six groups: 'recognized diabetes' (a diabetes diagnostic code or any diabetes medication), 'probable diabetes' (maximum glucose ≥ 11.1 mmol L(-1)), 'possible diabetes' (maximum glucose between 7.8 and 11.1 mmol L(-1)), 'unlikely diabetes' (maximum glucose between 6.0 and 7.8 mmol L(-1)), 'no diabetes' (maximum glucose < 6.0 mmol L(-1)) and 'unknown diabetes status' (no glucose test). We compared this electronic classification to a reference standard chart review performed by a blinded abstractor.
RESULTS: A total of 500 hospitalizations were included. The prevalence of each diabetes group was: recognized - 17%; probable - 4%; possible - 15%; unlikely - 20%; none - 15%; and unknown - 29%. Our electronic algorithm correctly classified 88.8% (95% confidence interval 85.7-91.3) of hospitalizations (weighted-Kappa = 0.885; 95% confidence interval 0.851-0.919). The sensitivity, specificity and positive predictive values of our algorithm for 'known diabetes' was 0.842, 0.988 and 0.941, respectively. For patients at a 'high risk for diabetes' (maximum glucose > .8 mmol L(-1)), the corresponding values were 0.921, 0.971 and 0.872.
CONCLUSIONS: Patients with diagnosed and undiagnosed diabetes can be accurately identified using electronic health care data.
© 2011 Blackwell Publishing Ltd.

Entities:  

Mesh:

Year:  2011        PMID: 21332609     DOI: 10.1111/j.1365-2753.2011.01633.x

Source DB:  PubMed          Journal:  J Eval Clin Pract        ISSN: 1356-1294            Impact factor:   2.431


  9 in total

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Review 4.  Leveraging Healthcare System Data to Identify High-Risk Dyslipidemia Patients.

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Authors:  Luke V Rasmussen; Will K Thompson; Jennifer A Pacheco; Abel N Kho; David S Carrell; Jyotishman Pathak; Peggy L Peissig; Gerard Tromp; Joshua C Denny; Justin B Starren
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6.  Distinguishing incident and prevalent diabetes in an electronic medical records database.

Authors:  Ronac Mamtani; Kevin Haynes; Brian S Finkelman; Frank I Scott; James D Lewis
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7.  A rule-based electronic phenotyping algorithm for detecting clinically relevant cardiovascular disease cases.

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9.  Assessing electronic health record phenotypes against gold-standard diagnostic criteria for diabetes mellitus.

Authors:  Susan E Spratt; Katherine Pereira; Bradi B Granger; Bryan C Batch; Matthew Phelan; Michael Pencina; Marie Lynn Miranda; Ebony Boulware; Joseph E Lucas; Charlotte L Nelson; Benjamin Neely; Benjamin A Goldstein; Pamela Barth; Rachel L Richesson; Isaretta L Riley; Leonor Corsino; Eugenia R McPeek Hinz; Shelley Rusincovitch; Jennifer Green; Anna Beth Barton; Carly Kelley; Kristen Hyland; Monica Tang; Amanda Elliott; Ewa Ruel; Alexander Clark; Melanie Mabrey; Kay Lyn Morrissey; Jyothi Rao; Beatrice Hong; Marjorie Pierre-Louis; Katherine Kelly; Nicole Jelesoff
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  9 in total

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