Literature DB >> 21332152

One-pot strategies for the synthesis of the tetrasaccharide linkage region of proteoglycans.

Teng-Yi Huang1, Medel Manuel L Zulueta, Shang-Cheng Hung.   

Abstract

A linker-attached tetrasaccharide corresponding to the linkage region of proteoglycans was synthesized via one-pot procedures from the silylated monosaccharide derivatives. Regioselective one-pot protection protocols were applied in generating the requisite monosaccharide building blocks whereas stereoselective one-pot glycosylation approaches were utilized to assemble the tetrasaccharide skeleton.

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Year:  2011        PMID: 21332152     DOI: 10.1021/ol200192d

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  7 in total

Review 1.  Automated Chemical Oligosaccharide Synthesis: Novel Approach to Traditional Challenges.

Authors:  Matteo Panza; Salvatore G Pistorio; Keith J Stine; Alexei V Demchenko
Journal:  Chem Rev       Date:  2018-06-28       Impact factor: 60.622

2.  Chemical synthesis of syndecan-3 glycopeptides bearing two heparan sulfate glycan chains.

Authors:  Keisuke Yoshida; Bo Yang; Weizhun Yang; Zeren Zhang; Jicheng Zhang; Xuefei Huang
Journal:  Angew Chem Int Ed Engl       Date:  2014-06-30       Impact factor: 15.336

3.  Obstacles and solutions for chemical synthesis of syndecan-3 (53-62) glycopeptides with two heparan sulfate chains.

Authors:  Weizhun Yang; Keisuke Yoshida; Bo Yang; Xuefei Huang
Journal:  Carbohydr Res       Date:  2016-10-20       Impact factor: 2.104

4.  Synthesis of orthogonally protected bacterial, rare-sugar and D-glycosamine building blocks.

Authors:  Madhu Emmadi; Suvarn S Kulkarni
Journal:  Nat Protoc       Date:  2013-09-05       Impact factor: 13.491

5.  Chemical synthesis of a heparan sulfate glycopeptide: syndecan-1.

Authors:  Bo Yang; Keisuke Yoshida; Zhaojun Yin; Hang Dai; Herbert Kavunja; Mohammad H El-Dakdouki; Suttipun Sungsuwan; Steven B Dulaney; Xuefei Huang
Journal:  Angew Chem Int Ed Engl       Date:  2012-09-07       Impact factor: 15.336

6.  Total synthesis of tetraacylated phosphatidylinositol hexamannoside and evaluation of its immunomodulatory activity.

Authors:  Pratap S Patil; Ting-Jen Rachel Cheng; Medel Manuel L Zulueta; Shih-Ting Yang; Larry S Lico; Shang-Cheng Hung
Journal:  Nat Commun       Date:  2015-06-03       Impact factor: 14.919

7.  Chemical synthesis of human syndecan-4 glycopeptide bearing O-, N-sulfation and multiple aspartic acids for probing impacts of the glycan chain and the core peptide on biological functions.

Authors:  Weizhun Yang; Yigitcan Eken; Jicheng Zhang; Logan Emerson Cole; Sherif Ramadan; Yongmei Xu; Zeren Zhang; Jian Liu; Angela K Wilson; Xuefei Huang
Journal:  Chem Sci       Date:  2020-05-11       Impact factor: 9.825

  7 in total

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