| Literature DB >> 21332151 |
Fangrui Zhong1, Youqing Wang, Xiaoyu Han, Kuo-Wei Huang, Yixin Lu.
Abstract
A series of novel bifunctional phosphine-sulfonamide organic catalysts were designed and readily prepared from natural amino acids, and they were utilized to promote enantioselective aza-Morita-Baylis-Hillman (MBH) reactions. L-threonine-derived phosphine-sulfonamide 9b was found to be the most efficient catalyst, affording the desired aza-MBH adducts in high yields and with excellent enantioselectivities.Entities:
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Year: 2011 PMID： 21332151 DOI： 10.1021/ol103145g
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005