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Literature DB >> 21331513

Expression of mucins on the mucosal surface of lungs of 4-week-old pigs.

Chung Hyun Kim¹, Kichan Lee, Kiwon Han, Yeonsu Oh, Duyeol Kim, Hwi Won Seo, Changhoon Park, Mi-Kyoung Ha, Sung-Hoon Kim, Kyung-Dong Cho, Bog-Hieu Lee, Chanhee Chae.

Abstract

The aim of this study was to determine the immunoreactivity of normal small bronchial, bronchiolar, respiratory bronchiolar, and interalveolar epithelium using antibodies to six mucins: MUC1, MUC2, MUC4, MUC5AC, MUC5B, and MUC6. The large, gel-forming secreted mucins MUC2, MUC5AC, and MUC5B were widely expressed in the lower respiratory tract. The results of this study demonstrate that these secreted mucins form a gel to cover and protect the mucosal surface in the lower respiratory tract of pigs. © Springer Science+Business Media B.V. 2011

Entities: Gene Species

Mesh：

Substances：
Mucins

Year: 2011 PMID： 21331513 DOI： 10.1007/s11259-011-9465-y

Source DB: PubMed Journal: Vet Res Commun ISSN： 0165-7380 Impact factor: 2.459

10 in total

1. 2000 Report of the AVMA Panel on Euthanasia.

Authors:
Journal: J Am Vet Med Assoc Date: 2001-03-01 Impact factor: 1.936

Review 2. Mucins in cancer: protection and control of the cell surface.

Authors: Michael A Hollingsworth; Benjamin J Swanson
Journal: Nat Rev Cancer Date: 2004-01 Impact factor: 60.716

Review 3. Respiratory tract mucin genes and mucin glycoproteins in health and disease.

Authors: Mary Callaghan Rose; Judith A Voynow
Journal: Physiol Rev Date: 2006-01 Impact factor: 37.312

4. Strategies for improving the immunohistochemical staining of various intranuclear prognostic markers in formalin-paraffin sections: androgen receptor, estrogen receptor, progesterone receptor, p53 protein, proliferating cell nuclear antigen, and Ki-67 antigen revealed by antigen retrieval techniques.

Authors: C R Taylor; S R Shi; B Chaiwun; L Young; S A Imam; R J Cote
Journal: Hum Pathol Date: 1994-03 Impact factor: 3.466

5. MUC5AC, but not MUC2, is a prominent mucin in respiratory secretions.

Authors: H W Hovenberg; J R Davies; A Herrmann; C J Lindén; I Carlstedt
Journal: Glycoconj J Date: 1996-10 Impact factor: 2.916

6. Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease.

Authors: J D Li; A F Dohrman; M Gallup; S Miyata; J R Gum; Y S Kim; J A Nadel; A Prince; C B Basbaum
Journal: Proc Natl Acad Sci U S A Date: 1997-02-04 Impact factor: 11.205

1 in total

Review 1. Regulation of the Intestinal Barrier Function by Host Defense Peptides.

Authors: Kelsy Robinson; Zhuo Deng; Yongqing Hou; Guolong Zhang
Journal: Front Vet Sci Date: 2015-11-23

1 in total

Expression of mucins on the mucosal surface of lungs of 4-week-old pigs.

1. 2000 Report of the AVMA Panel on Euthanasia.

Review 2. Mucins in cancer: protection and control of the cell surface.

Review 3. Respiratory tract mucin genes and mucin glycoproteins in health and disease.

5. MUC5AC, but not MUC2, is a prominent mucin in respiratory secretions.

6. Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease.

7. Pseudomyxoma peritonei is a disease of MUC2-expressing goblet cells.

8. Expression of mucins in the mucosal surface of small intestines in 1 week-old pigs.

9. Expression of conserved mucin domains by epithelial tissues in various mammalian species.

Review 10. Mucins: structure, function, and role in pulmonary diseases.

Review 1. Regulation of the Intestinal Barrier Function by Host Defense Peptides.