Literature DB >> 21331512

Neurogenic heterotopic ossification: epidemiology and morphology on conventional radiographs in an early neurological rehabilitation population.

R Seipel1, S Langner, T Platz, M Lippa, J P Kuehn, N Hosten.   

Abstract

OBJECTIVE: To retrospectively evaluate neurogenic heterotopic ossification in an early neurological rehabilitation population (phases B and C) with respect to epidemiology and morphology on conventional radiographs.
MATERIALS AND METHODS: Over a 4-year period, 1,463 patients treated at a clinic for early neurological rehabilitation were evaluated for clinical symptoms of neurogenic heterotopic ossification. In case of clinical suspicion, plain radiographs of the expected sites were obtained. If heterotopic ossification was detected, the initial and subsequent radiographs were retrospectively analyzed for sites, size, and morphology. Immature lesions were categorized as small (<10 mm) or large (10-100 mm).
RESULTS: The prevalence rate of neurogenic heterotopic ossification was 2.05%. The condition was most common in young male adults. The hip was the most common site accounting for more than half of the cases. Two or more ossifications were seen in 56.7% of the affected patients with approximately two-thirds showing bilateral symmetric involvement of corresponding joint regions. The size of ossifications strongly varied interindividually. Small immature lesions demonstrated less progression in size than large lesions during maturation (P < 0.05).
CONCLUSION: Standard radiographs, as a fast and inexpensive technique, allow the expected size progression of heterotopic ossifications during maturation to be estimated, which is relevant in terms of therapeutic decisions, patient mobilization, and neurological rehabilitation.

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Year:  2011        PMID: 21331512     DOI: 10.1007/s00256-011-1115-5

Source DB:  PubMed          Journal:  Skeletal Radiol        ISSN: 0364-2348            Impact factor:   2.199


  22 in total

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Journal:  Br J Radiol       Date:  1990-10       Impact factor: 3.039

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3.  Neurogenic heterotopic ossification : a diagnostic and therapeutic challenge in neurorehabilitation.

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Journal:  Arch Phys Med Rehabil       Date:  1986-05       Impact factor: 3.966

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Journal:  Skeletal Radiol       Date:  1979-04-10       Impact factor: 2.199

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Review 7.  Heterotopic ossification following traumatic brain injury and spinal cord injury.

Authors:  Cara A Cipriano; Stephan G Pill; Mary Ann Keenan
Journal:  J Am Acad Orthop Surg       Date:  2009-11       Impact factor: 3.020

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Journal:  Clin Orthop Relat Res       Date:  1991-02       Impact factor: 4.176

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Journal:  Clin Orthop Relat Res       Date:  1991-02       Impact factor: 4.176

Review 10.  Achilles tendon ossification: pathology, imaging and aetiology.

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Journal:  Disabil Rehabil       Date:  2008       Impact factor: 3.033

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  8 in total

1.  Functional Outcomes of the Surgery and Rehabilitation in a Challenging Case of Heterotopic Ossification after Encephalitis.

Authors:  T Ekiz; M Doğan Aslan; S Özbudak Demir; M Altay; N Özgirgin
Journal:  West Indian Med J       Date:  2015-04-14       Impact factor: 0.171

2.  Early detection of heterotopic ossification using near-infrared optical imaging reveals dynamic turnover and progression of mineralization following Achilles tenotomy and burn injury.

Authors:  Joseph E Perosky; Jonathan R Peterson; Owulatobi N Eboda; Michael D Morris; Stewart C Wang; Benjamin Levi; Kenneth M Kozloff
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3.  Pelvic heterotopic ossification: when CT comes to the aid of MR imaging.

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Journal:  Insights Imaging       Date:  2013-07-05

Review 4.  Neurological heterotopic ossification: novel mechanisms, prognostic biomarkers and prophylactic therapies.

Authors:  Ker Rui Wong; Richelle Mychasiuk; Terence J O'Brien; Sandy R Shultz; Stuart J McDonald; Rhys D Brady
Journal:  Bone Res       Date:  2020-12-09       Impact factor: 13.567

5.  Comparison of magnetic resonance imaging and computed tomography for bone assessment of neurogenic heterotopic ossification of the hip: a preliminary study.

Authors:  Raphaël Amar; Tristan Thiry; Marjorie Salga; Dominique Safa; Annaëlle Chetrit; Laure Gatin; Robert-Yves Carlier
Journal:  J Orthop Surg Res       Date:  2021-12-20       Impact factor: 2.359

Review 6.  Acquired heterotopic ossification in hips and knees following encephalitis: case report and literature review.

Authors:  Xianghong Zhang; Shuo Jie; Tang Liu; Xiangsheng Zhang
Journal:  BMC Surg       Date:  2014-10-03       Impact factor: 2.102

7.  MRI Findings of Early Myositis Ossificans without Calcification or Ossification.

Authors:  Hexiang Wang; Pei Nie; Yang Li; Feng Hou; Cheng Dong; Yonghua Huang; Dapeng Hao
Journal:  Biomed Res Int       Date:  2018-09-03       Impact factor: 3.411

8.  Potential genes and pathways associated with heterotopic ossification derived from analyses of gene expression profiles.

Authors:  Zhanyu Yang; Delong Liu; Rui Guan; Xin Li; Yiwei Wang; Bin Sheng
Journal:  J Orthop Surg Res       Date:  2021-08-14       Impact factor: 2.359

  8 in total

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