| Literature DB >> 21331241 |
Yuji Ikegaya1, Naoya Takahashi.
Abstract
Synchronized spikes prevail in cortical networks, and their modulations are associated with attention, sensory processing and motor behaviors, yet it remained unclear how spikes can synchronize at the millisecond precision in a noisy network. Our new evidence shows that neurons do not easily synchronize; rather, in order to make them generate synchronous spikes, "parent" presynaptic neurons commonly shared by them are required to synchronize in advance. Therefore, the conventional style of neurophysiological research is unable to reach the true origin of synchronization.Entities:
Keywords: action potential; brain; circuit; network; neuron; synapse; synchrony
Year: 2010 PMID: 21331241 PMCID: PMC3038065 DOI: 10.4161/cib.3.6.12980
Source DB: PubMed Journal: Commun Integr Biol ISSN: 1942-0889