Literature DB >> 21331241

Return to forever: Finding the origin of neural synchrony.

Yuji Ikegaya1, Naoya Takahashi.   

Abstract

Synchronized spikes prevail in cortical networks, and their modulations are associated with attention, sensory processing and motor behaviors, yet it remained unclear how spikes can synchronize at the millisecond precision in a noisy network. Our new evidence shows that neurons do not easily synchronize; rather, in order to make them generate synchronous spikes, "parent" presynaptic neurons commonly shared by them are required to synchronize in advance. Therefore, the conventional style of neurophysiological research is unable to reach the true origin of synchronization.

Entities:  

Keywords:  action potential; brain; circuit; network; neuron; synapse; synchrony

Year:  2010        PMID: 21331241      PMCID: PMC3038065          DOI: 10.4161/cib.3.6.12980

Source DB:  PubMed          Journal:  Commun Integr Biol        ISSN: 1942-0889


  16 in total

1.  Stable propagation of synchronous spiking in cortical neural networks.

Authors:  M Diesmann; M O Gewaltig; A Aertsen
Journal:  Nature       Date:  1999-12-02       Impact factor: 49.962

2.  Pyramidal cell communication within local networks in layer 2/3 of rat neocortex.

Authors:  Carl Holmgren; Tibor Harkany; Björn Svennenfors; Yuri Zilberter
Journal:  J Physiol       Date:  2003-06-17       Impact factor: 5.182

3.  Circuit topology for synchronizing neurons in spontaneously active networks.

Authors:  Naoya Takahashi; Takuya Sasaki; Wataru Matsumoto; Norio Matsuki; Yuji Ikegaya
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-17       Impact factor: 11.205

4.  Geometric and functional organization of cortical circuits.

Authors:  Gordon M G Shepherd; Armen Stepanyants; Ingrid Bureau; Dmitri Chklovskii; Karel Svoboda
Journal:  Nat Neurosci       Date:  2005-05-08       Impact factor: 24.884

5.  Dynamics and effective topology underlying synchronization in networks of cortical neurons.

Authors:  Danny Eytan; Shimon Marom
Journal:  J Neurosci       Date:  2006-08-16       Impact factor: 6.167

6.  Cortical feed-forward networks for binding different streams of sensory information.

Authors:  Björn M Kampa; Johannes J Letzkus; Greg J Stuart
Journal:  Nat Neurosci       Date:  2006-11-12       Impact factor: 24.884

Review 7.  Watching neuronal circuit dynamics through functional multineuron calcium imaging (fMCI).

Authors:  Naoya Takahashi; Takuya Sasaki; Atsushi Usami; Norio Matsuki; Yuji Ikegaya
Journal:  Neurosci Res       Date:  2007-03-13       Impact factor: 3.304

8.  Reverse optical trawling for synaptic connections in situ.

Authors:  Takuya Sasaki; Genki Minamisawa; Naoya Takahashi; Norio Matsuki; Yuji Ikegaya
Journal:  J Neurophysiol       Date:  2009-04-22       Impact factor: 2.714

9.  Population imaging of ongoing neuronal activity in the visual cortex of awake rats.

Authors:  David S Greenberg; Arthur R Houweling; Jason N D Kerr
Journal:  Nat Neurosci       Date:  2008-06-15       Impact factor: 24.884

10.  Highly nonrandom features of synaptic connectivity in local cortical circuits.

Authors:  Sen Song; Per Jesper Sjöström; Markus Reigl; Sacha Nelson; Dmitri B Chklovskii
Journal:  PLoS Biol       Date:  2005-03-01       Impact factor: 8.029

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