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Literature DB >> 21331030

Genomics: Drugs, diabetes and cancer.

Morris J Birnbaum, Reuben J Shaw.

Abstract

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2011 PMID： 21331030 PMCID： PMC4237313 DOI： 10.1038/470338a

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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14 in total

1. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.

Authors: Reuben J Shaw; Katja A Lamia; Debbie Vasquez; Seung-Hoi Koo; Nabeel Bardeesy; Ronald A Depinho; Marc Montminy; Lewis C Cantley
Journal: Science Date: 2005-11-24 Impact factor: 47.728

2. An unusual form of diabetes mellitus in ataxia telangiectasia.

Authors: D S Schalch; D E McFarlin; M H Barlow
Journal: N Engl J Med Date: 1970-06-18 Impact factor: 91.245

Review 3. An energetic tale of AMPK-independent effects of metformin.

Authors: Russell A Miller; Morris J Birnbaum
Journal: J Clin Invest Date: 2010-06-23 Impact factor: 14.808

4. Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1.

Authors: D Q Yang; M B Kastan
Journal: Nat Cell Biol Date: 2000-12 Impact factor: 28.824

5. ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.

Authors: Jochen G Schneider; Brian N Finck; Jie Ren; Kara N Standley; Masatoshi Takagi; Kirsteen H Maclean; Carlos Bernal-Mizrachi; Anthony J Muslin; Michael B Kastan; Clay F Semenkovich
Journal: Cell Metab Date: 2006-11 Impact factor: 27.287

6. Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.

Authors: Gopal P Sapkota; Maria Deak; Agnieszka Kieloch; Nick Morrice; Aaron A Goodarzi; Carl Smythe; Yosef Shiloh; Susan P Lees-Miller; Dario R Alessi
Journal: Biochem J Date: 2002-12-01 Impact factor: 3.857

7. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression.

Authors: David B Shackelford; Reuben J Shaw
Journal: Nat Rev Cancer Date: 2009-08 Impact factor: 60.716

8. Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene.

Authors: Richard S Legro; Huiman X Barnhart; William D Schlaff; Bruce R Carr; Michael P Diamond; Sandra A Carson; Michael P Steinkampf; Christos Coutifaris; Peter G McGovern; Nicholas A Cataldo; Gabriella G Gosman; John E Nestler; Linda C Giudice; Kathryn G Ewens; Richard S Spielman; Phyllis C Leppert; Evan R Myers
Journal: J Clin Endocrinol Metab Date: 2007-11-13 Impact factor: 5.958

9. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Authors: Shuhei Matsuoka; Bryan A Ballif; Agata Smogorzewska; E Robert McDonald; Kristen E Hurov; Ji Luo; Corey E Bakalarski; Zhenming Zhao; Nicole Solimini; Yaniv Lerenthal; Yosef Shiloh; Steven P Gygi; Stephen J Elledge
Journal: Science Date: 2007-05-25 Impact factor: 47.728

10. Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.

Authors: Kaixin Zhou; Celine Bellenguez; Chris C A Spencer; Amanda J Bennett; Ruth L Coleman; Roger Tavendale; Simon A Hawley; Louise A Donnelly; Chris Schofield; Christopher J Groves; Lindsay Burch; Fiona Carr; Amy Strange; Colin Freeman; Jenefer M Blackwell; Elvira Bramon; Matthew A Brown; Juan P Casas; Aiden Corvin; Nicholas Craddock; Panos Deloukas; Serge Dronov; Audrey Duncanson; Sarah Edkins; Emma Gray; Sarah Hunt; Janusz Jankowski; Cordelia Langford; Hugh S Markus; Christopher G Mathew; Robert Plomin; Anna Rautanen; Stephen J Sawcer; Nilesh J Samani; Richard Trembath; Ananth C Viswanathan; Nicholas W Wood; Lorna W Harries; Andrew T Hattersley; Alex S F Doney; Helen Colhoun; Andrew D Morris; Calum Sutherland; D Grahame Hardie; Leena Peltonen; Mark I McCarthy; Rury R Holman; Colin N A Palmer; Peter Donnelly; Ewan R Pearson
Journal: Nat Genet Date: 2010-12-26 Impact factor: 38.330

14 in total

1. Metformin impairs the growth of liver kinase B1-intact cervical cancer cells.

Authors: Xuxian Xiao; Qiongqiong He; Changming Lu; Kaitlin D Werle; Rui-Xun Zhao; Jianfeng Chen; Ben C Davis; Rutao Cui; Jiyong Liang; Zhi-Xiang Xu
Journal: Gynecol Oncol Date: 2012-06-24 Impact factor: 5.482

2. The association and joint effect of serum cholesterol, glycemic status with the risk of incident cancer among middle-aged and elderly population in china cardiometabolic disease and cancer cohort (4C)-study.

Authors: Mian Li; Jieli Lu; Jing Fu; Qin Wan; Tiange Wang; Yanan Huo; Yu Xu; Min Xu; Zhiyun Zhao; Yuhong Chen; Shuangyuan Wang; Guijun Qin; Yingfen Qin; Ruying Hu; Xulei Tang; Guixia Wang; Feixia Shen; Zuojie Luo; Li Chen; Qing Su; Xuefeng Yu; Li Yan; Gang Chen; Zhengnan Gao; Yinfei Zhang; Chao Liu; Youmin Wang; Shengli Wu; Tao Yang; Qiang Li; Yiming Mu; Jiajun Zhao; Lulu Chen; Lixin Shi; Guang Ning; Yufang Bi; Hongyang Wang; Weiqing Wang
Journal: Am J Cancer Res Date: 2020-03-01 Impact factor: 6.166

Review 3. Insulin signaling and insulin resistance.

Authors: Elmus G Beale
Journal: J Investig Med Date: 2013-01 Impact factor: 2.895

4. Gerosuppressant metformin: less is more.

Authors: Javier A Menendez; Sílvia Cufí; Cristina Oliveras-Ferraros; Luciano Vellon; Jorge Joven; Alejandro Vazquez-Martin
Journal: Aging (Albany NY) Date: 2011-04 Impact factor: 5.682

Review 5. Metformin: multi-faceted protection against cancer.

Authors: Sonia Del Barco; Alejandro Vazquez-Martin; Sílvia Cufí; Cristina Oliveras-Ferraros; Joaquim Bosch-Barrera; Jorge Joven; Begoña Martin-Castillo; Javier A Menendez
Journal: Oncotarget Date: 2011-12

Review 6. Recent progress in targeting cancer.

Authors: Zoya N Demidenko; James A McCubrey
Journal: Aging (Albany NY) Date: 2011-12 Impact factor: 5.682

Review 7. Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer.

Authors: Javier A Menendez; Sílvia Cufí; Cristina Oliveras-Ferraros; Begoña Martin-Castillo; Jorge Joven; Luciano Vellon; Alejandro Vazquez-Martin
Journal: Aging (Albany NY) Date: 2011-11 Impact factor: 5.682