INTRODUCTION: The study sought to ascertain the prevalence of the aetiological agents of genital discharge and genital ulcer diseases in Maputo, Mozambique. METHODOLOGY: Consecutive consenting patients presenting to the Centro de Saúde do Porto in Maputo between March and April 2005 with genital discharge syndrome and/or genital ulcer diseases were recruited. Specimens were collected for the identification of STI pathogens. RESULTS: Of 346 recruited patients, 164 were male and 182 female. The prevalence of confirmed single aetiological agents for male urethritis was as follows: N. gonorrhoeae, 35%; C. trachomatis, 10%; and M. genitalium 4%. For vaginal discharge, N. gonorrhoeae was found in 11% of the women tested, followed by C. trachomatis (6.5%), bacterial vaginosis (34%), and T. vaginalis (2%). The prevalence of genital ulcers was as follows: Herpes simplex virus type 2, 62%; H. ducreyi 4 %; and C. trachomatis biovar LGV, 4%. Five percent of patients with genital ulcers had a positive syphilis serology (RPR ≥ 1:8 and confirmed by TPHA) and 35% of all tested patients were HIV-1/2 infected. Cases of mixed infections were present in 5%, 11% and 3% of patients with male urethritis, vaginal discharge, and genital ulcers respectively. CONCLUSION: The classic sexually transmitted infection aetiologies are still prevalent in Maputo. The study highlights the need for a periodic surveillance to inform syndromic management protocols.
INTRODUCTION: The study sought to ascertain the prevalence of the aetiological agents of genital discharge and genital ulcer diseases in Maputo, Mozambique. METHODOLOGY: Consecutive consenting patients presenting to the Centro de Saúde do Porto in Maputo between March and April 2005 with genital discharge syndrome and/or genital ulcer diseases were recruited. Specimens were collected for the identification of STI pathogens. RESULTS: Of 346 recruited patients, 164 were male and 182 female. The prevalence of confirmed single aetiological agents for male urethritis was as follows: N. gonorrhoeae, 35%; C. trachomatis, 10%; and M. genitalium 4%. For vaginal discharge, N. gonorrhoeae was found in 11% of the women tested, followed by C. trachomatis (6.5%), bacterial vaginosis (34%), and T. vaginalis (2%). The prevalence of genital ulcers was as follows: Herpes simplex virus type 2, 62%; H. ducreyi 4 %; and C. trachomatis biovar LGV, 4%. Five percent of patients with genital ulcers had a positive syphilis serology (RPR ≥ 1:8 and confirmed by TPHA) and 35% of all tested patients were HIV-1/2 infected. Cases of mixed infections were present in 5%, 11% and 3% of patients with male urethritis, vaginal discharge, and genital ulcers respectively. CONCLUSION: The classic sexually transmitted infection aetiologies are still prevalent in Maputo. The study highlights the need for a periodic surveillance to inform syndromic management protocols.
Authors: Cornelis A Rietmeijer; More Mungati; Peter H Kilmarx; Beth Tippett Barr; Elizabeth Gonese; Ranmini S Kularatne; David A Lewis; Jeffrey D Klausner; Luanne Rodgers; H Hunter Handsfield Journal: Sex Transm Dis Date: 2019-09 Impact factor: 2.830
Authors: More Mungati; Anna Machiha; Owen Mugurungi; Mufuta Tshimanga; Peter H Kilmarx; Justice Nyakura; Gerald Shambira; Vitalis Kupara; David A Lewis; Elizabeth Gonese; Beth A Tippett Barr; H Hunter Handsfield; Cornelis A Rietmeijer Journal: Sex Transm Dis Date: 2018-01 Impact factor: 2.830
Authors: Peter H Kilmarx; Elizabeth Gonese; David A Lewis; Z Mike Chirenje; Beth A Tippett Barr; Ahmed S Latif; Lovemore Gwanzura; H Hunter Handsfield; Anna Machiha; Owen Mugurungi; Cornelius A Rietmeijer Journal: PLoS One Date: 2018-06-11 Impact factor: 3.240