| Literature DB >> 21329708 |
Enikö Sonkoly1, Andor Pivarcsi.
Abstract
MicroRNAs (miRNAs) are small noncoding RNAs that regulate basic biological processes by posttranscriptional suppression of their target genes. Altered miRNA expression may lead to widespread gene expression changes and has been implicated in pathophysiological processes such as cancer and inflammation. In this review, we summarize the present knowledge about the role of miRNAs in inflammation and in the response to environmental agents and pollutants, such as cigarette smoke, ethanol, carcinogenic chemicals such as benzo(a)pyrene (BaP) and dioxin, and UV radiation. Copyright ÂEntities:
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Year: 2011 PMID: 21329708 DOI: 10.1016/j.mrfmmm.2011.02.002
Source DB: PubMed Journal: Mutat Res ISSN: 0027-5107 Impact factor: 2.433