Literature DB >> 21328235

[Polypharmacy is an indicator for a poor prognosis, which is not altered by deprescribing in nursing home].

T Schönenberger1, S Rauber, N Hauser, M Roth, A Wettstein, P M Schönenberger.   

Abstract

AIM: To examine the influence of polypharmacy ordered by the pretreating site and deprescribing (i.e. the appropriate withdrawal of prescribed drugs) by the nursing home physician on survival time.
METHODS: Retrospective Analysis of medical databasis from 1,249 patients, thereof 611 in a nursing home with practice of deprescribing.
RESULTS: 70% of the patients with excessive polypharmacy (>9 drugs), 57% of those with polypharmacy (6 to 9 drugs) and 43% of the remaining patients (<6 drugs) deceased within 286 days after admission (chi-squared 2 DF = 43.72; p <0.001). Deprescribing by the nursing home physician at admission revealed no influence on survival time.
CONCLUSION: Polypharmacy is not the reason, but an indicator for a poor prognosis, which is not altered by deprescribing.

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Year:  2011        PMID: 21328235     DOI: 10.1024/1661-8157/a000431

Source DB:  PubMed          Journal:  Praxis (Bern 1994)        ISSN: 1661-8157


  1 in total

1.  Excessive polypharmacy and survival in polypathological patients.

Authors:  Jesús Díez-Manglano; Mercedes Giménez-López; Vanesa Garcés-Horna; María Sevil-Puras; Elena Castellar-Otín; Paloma González-García; Isabel Fiteni-Mera; Teresa Morlanes-Navarro
Journal:  Eur J Clin Pharmacol       Date:  2015-04-26       Impact factor: 2.953

  1 in total

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