Literature DB >> 21327597

Analyzing the cryptome: uncovering secret sequences.

Parimal Samir1, Andrew J Link.   

Abstract

The mammalian cryptome consists of bioactive peptides generated by the proteolysis of precursor proteins. It is speculated that the cryptide repertoire increases the complexity of the proteome by an order of magnitude. Cryptides have been found to function in a wide range of processes including neuronal signaling, antigen presentation, and the inflammatory response. Due to their potential as therapeutic agents, there has been an increasing interest in studying cryptides. In this review, we discuss different approaches for discovering these hidden peptides and how proteomic tools can be utilized to aid in their identification and characterization.

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Year:  2011        PMID： 21327597      PMCID： PMC3085711          DOI： 10.1208/s12248-011-9252-2

Source DB:  PubMed          Journal:  AAPS J        ISSN： 1550-7416            Impact factor:   4.009


  66 in total

1.  Cell adhesive sequences in mouse laminin beta1 chain.

Authors:  M Nomizu; Y Kuratomi; M L Ponce; S Y Song; K Miyoshi; A Otaka; S K Powell; M P Hoffman; H K Kleinman; Y Yamada
Journal:  Arch Biochem Biophys       Date:  2000-06-15       Impact factor: 4.013

2.  Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor.

Authors:  S Nakanishi; A Inoue; T Kita; M Nakamura; A C Chang; S N Cohen; S Numa
Journal:  Nature       Date:  1979-03-29       Impact factor: 49.962

3.  The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications.

Authors:  Donald S Kirkpatrick; Scott A Gerber; Steven P Gygi
Journal:  Methods       Date:  2005-01-12       Impact factor: 3.608

4.  Identifying the proteins to which small-molecule probes and drugs bind in cells.

Authors:  Shao-En Ong; Monica Schenone; Adam A Margolin; Xiaoyu Li; Kathy Do; Mary K Doud; D R Mani; Letian Kuai; Xiang Wang; John L Wood; Nicola J Tolliday; Angela N Koehler; Lisa A Marcaurelle; Todd R Golub; Robert J Gould; Stuart L Schreiber; Steven A Carr
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-02       Impact factor: 11.205

5.  Profiling of endogenous peptides by multidimensional liquid chromatography: On-line automated sample cleanup for biomarker discovery in human urine.

Authors:  Egidijus Machtejevas; Gyorgy Marko-Varga; Claes Lindberg; Dieter Lubda; Robertus Hendriks; Klaus K Unger
Journal:  J Sep Sci       Date:  2009-07       Impact factor: 3.645

6.  Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics.

Authors:  Paola Picotti; Bernd Bodenmiller; Lukas N Mueller; Bruno Domon; Ruedi Aebersold
Journal:  Cell       Date:  2009-08-06       Impact factor: 41.582

7.  Direct analysis of protein complexes using mass spectrometry.

Authors:  A J Link; J Eng; D M Schieltz; E Carmack; G J Mize; D R Morris; B M Garvik; J R Yates
Journal:  Nat Biotechnol       Date:  1999-07       Impact factor: 54.908

8.  Parstatin, the cleaved peptide on proteinase-activated receptor 1 activation, is a potent inhibitor of angiogenesis.

Authors:  Panagiota Zania; Despina Gourni; Alfred C Aplin; Roberto F Nicosia; Christodoulos S Flordellis; Michael E Maragoudakis; Nikos E Tsopanoglou
Journal:  J Pharmacol Exp Ther       Date:  2008-11-06       Impact factor: 4.030

9.  Quantitation of neuropeptides in Cpe(fat)/Cpe(fat) mice using differential isotopic tags and mass spectrometry.

Authors:  Fa-yun Che; Lloyd D Fricker
Journal:  Anal Chem       Date:  2002-07-01       Impact factor: 6.986

10.  Human hemoglobin-derived peptides exhibit antimicrobial activity: a class of host defense peptides.

Authors:  Cornelia Liepke; Susann Baxmann; Cornelia Heine; Nicole Breithaupt; Ludger Ständker; Wolf-Georg Forssmann
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2003-07-05       Impact factor: 3.205
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  10 in total

Review 1.  The Plant Peptidome: An Expanding Repertoire of Structural Features and Biological Functions.

Authors:  Patrizia Tavormina; Barbara De Coninck; Natalia Nikonorova; Ive De Smet; Bruno P A Cammue
Journal:  Plant Cell       Date:  2015-08-14       Impact factor: 11.277

2.  Peptides of the constant region of antibodies display fungicidal activity.

Authors:  Luciano Polonelli; Tecla Ciociola; Walter Magliani; Pier Paolo Zanello; Tiziana D'Adda; Serena Galati; Flavia De Bernardis; Silvia Arancia; Elena Gabrielli; Eva Pericolini; Anna Vecchiarelli; Denise C Arruda; Marcia R Pinto; Luiz R Travassos; Thelma A Pertinhez; Alberto Spisni; Stefania Conti
Journal:  PLoS One       Date:  2012-03-21       Impact factor: 3.240

3.  Antibody Peptide based antifungal immunotherapy.

Authors:  Walter Magliani; Stefania Conti; Laura Giovati; Pier Paolo Zanello; Martina Sperindè; Tecla Ciociola; Luciano Polonelli
Journal:  Front Microbiol       Date:  2012-06-01       Impact factor: 5.640

4.  A Naturally Occurring Antibody Fragment Neutralizes Infectivity of Diverse Infectious Agents.

Authors:  Luciano Polonelli; Tecla Ciociola; Lisa Elviri; Pier Paolo Zanello; Laura Giovati; Denise C Arruda; Julián E Muñoz; Renato A Mortara; Giulia Morace; Elisa Borghi; Serena Galati; Oriano Marin; Claudio Casoli; Elisabetta Pilotti; Paola Ronzi; Luiz R Travassos; Walter Magliani; Stefania Conti
Journal:  Sci Rep       Date:  2016-10-11       Impact factor: 4.379

Review 5.  Biostimulants in Plant Science: A Global Perspective.

Authors:  Oleg I Yakhin; Aleksandr A Lubyanov; Ildus A Yakhin; Patrick H Brown
Journal:  Front Plant Sci       Date:  2017-01-26       Impact factor: 5.753

Review 6.  Peptidome: Chaos or Inevitability.

Authors:  Irina Lyapina; Vadim Ivanov; Igor Fesenko
Journal:  Int J Mol Sci       Date:  2021-12-04       Impact factor: 5.923

7.  Metabolism of cryptic peptides derived from neuropeptide FF precursors: the involvement of insulin-degrading enzyme.

Authors:  Giuseppe Grasso; Przemyslaw Mielczarek; Magdalena Niedziolka; Jerzy Silberring
Journal:  Int J Mol Sci       Date:  2014-09-22       Impact factor: 5.923

Review 8.  The Role of Peptide Signals Hidden in the Structure of Functional Proteins in Plant Immune Responses.

Authors:  Irina Lyapina; Anna Filippova; Igor Fesenko
Journal:  Int J Mol Sci       Date:  2019-09-05       Impact factor: 5.923

9.  Impact of a Single Point Mutation on the Antimicrobial and Fibrillogenic Properties of Cryptides from Human Apolipoprotein B.

Authors:  Rosa Gaglione; Giovanni Smaldone; Angela Cesaro; Mariano Rumolo; Maria De Luca; Rocco Di Girolamo; Luigi Petraccone; Pompea Del Vecchio; Rosario Oliva; Eugenio Notomista; Emilia Pedone; Angela Arciello
Journal:  Pharmaceuticals (Basel)       Date:  2021-06-29

Review 10.  Host Defense Peptides as Templates for Antifungal Drug Development.

Authors:  Virginia Basso; Dat Q Tran; André J Ouellette; Michael E Selsted
Journal:  J Fungi (Basel)       Date:  2020-10-23
  10 in total

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