Literature DB >> 2132733

Positron emission tomography in neuropsychiatric lupus erythematosus.

G Stoppe1, K Wildhagen, J W Seidel, G J Meyer, O Schober, P Heintz, H Künkel, H Deicher, H Hundeshagen.   

Abstract

We performed positron emission tomography (PET) using 18F-labeled 2-F-2-deoxyglucose in 13 patients with systemic lupus erythematosus (SLE). Ten of them had clinical signs of central nervous system involvement (NP-SLE). All patients with neurologic symptoms showed pathologic changes on PET, always in accordance with the clinical state. Three patients without neuropsychiatric manifestations had normal PETs. Computed tomography of the brain and magnetic resonance imaging proved to be less sensitive to both presence and localization of CNS lesions. We conclude that the combination of PET and MRI constitutes the most useful diagnostic procedure for NP-SLE.

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Year:  1990        PMID: 2132733     DOI: 10.1212/wnl.40.2.304

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  11 in total

1.  Abnormal brain diffusivity in patients with neuropsychiatric systemic lupus erythematosus.

Authors:  Gerlof P Th Bosma; Tom W J Huizinga; Simon P Mooijaart; Mark A Van Buchem
Journal:  AJNR Am J Neuroradiol       Date:  2003-05       Impact factor: 3.825

Review 2.  Current concepts of neuropsychiatric systemic lupus erythematosus (NP-SLE).

Authors:  R A Asherson; S D Denburg; J A Denburg; R M Carbotte; N Futrell
Journal:  Postgrad Med J       Date:  1993-08       Impact factor: 2.401

3.  Diagnosis and monitoring of central nervous system involvement in systemic lupus erythematosus: value of F-18 fluorodeoxyglucose PET.

Authors:  S M Weiner; A Otte; M Schumacher; R Klein; J Gutfleisch; I Brink; P Otto; E U Nitzsche; E Moser; H H Peter
Journal:  Ann Rheum Dis       Date:  2000-05       Impact factor: 19.103

4.  Brain single-photon emission tomography with 99mTc-HMPAO in neuropsychiatric systemic lupus erythematosus: relations with EEG and MRI findings and clinical manifestations.

Authors:  P Colamussi; M Giganti; C Cittanti; L Dovigo; F Trotta; M R Tola; R Tamarozzi; G Lucignani; A Piffanelli
Journal:  Eur J Nucl Med       Date:  1995-01

5.  Single photon emission computed tomography in systemic lupus erythematosus with psychiatric symptoms.

Authors:  K Kodama; S Okada; T Hino; K Takabayashi; Y Nawata; Y Uchida; N Yamanouchi; N Komatsu; T Ikeda; N Shinoda
Journal:  J Neurol Neurosurg Psychiatry       Date:  1995-03       Impact factor: 10.154

Review 6.  Neuropsychological impairment in systemic lupus erythematosus: a comparison with multiple sclerosis.

Authors:  R H B Benedict; J L Shucard; R Zivadinov; D W Shucard
Journal:  Neuropsychol Rev       Date:  2008-06-03       Impact factor: 7.444

7.  Fluctuating cognitive abnormalities and cerebral glucose metabolism in neuropsychiatric systemic lupus erythematosus.

Authors:  R M Carbotte; S D Denburg; J A Denburg; C Nahmias; E S Garnett
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-11       Impact factor: 10.154

8.  18FDG PET and acetazolamide-enhanced 99mTc-HMPAO SPET in systemic lupus erythematosus.

Authors:  F Grünwald; A Schomburg; A Badali; J Ruhlmann; L Pavics; H J Biersack
Journal:  Eur J Nucl Med       Date:  1995-09

Review 9.  Systemic lupus erythematosus involving the nervous system: presentation, pathogenesis, and management.

Authors:  Julia J Rhiannon
Journal:  Clin Rev Allergy Immunol       Date:  2008-06       Impact factor: 8.667

Review 10.  Controversies in lupus: nervous system involvement.

Authors:  G A Bruyn
Journal:  Ann Rheum Dis       Date:  1995-03       Impact factor: 19.103

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