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Literature DB >> 21327059

Immunization trials with an avian chlamydial MOMP gene recombinant adenovirus.

Changqing Qiu¹, Jizhang Zhou, Xiao-an Cao, Guozhen Lin, Fuying Zheng, Xiaowei Gong.

Abstract

Chicks were inoculated with a live vector vaccine of avian chlamydial MOMP gene recombinant adenovirus to evaluate efficacy, safety and viability of the vaccine. Five batches of the recombinant adenovirus vaccines, which were prepared using the 22nd generation avian chlamydial MOMP gene recombinant adenovirus cultured in HEK293 cells, were used to vaccinate 7 days-old chicks negative for chlamydial antibody. The recombinant adenovirus vaccine was shown to be both safe and effective in inducing specific immunity in vaccinated chicks.

Keywords: C. psittaci; chick; immunity; live recombinant adenovirus vaccine; major outer membrane protein gene; security

Mesh：

Substances：

Year: 2010 PMID： 21327059 PMCID： PMC3026466 DOI： 10.4161/bbug.1.4.12115

Source DB: PubMed Journal: Bioeng Bugs ISSN： 1949-1018

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