Literature DB >> 21327050

Stable mixed double donor chimerism: Absence of war doesn't necessarily mean peace.

Jens Gertow1, Jonas Mattsson J, Michael Uhlin.   

Abstract

Double cord blood transplantation has successfully been introduced to remedy the obstacle of a limited stem cell dose in a single cord blood graft. After a short initial period, the sustained hematopoiesis is derived almost exclusively from one of the donated units. In a recent publication in Clinical and Experimental Immunology we investigated two rare individuals in which both cord blood units co-existed for more than two years after transplantation.

Entities:  

Mesh:

Year:  2010        PMID: 21327050      PMCID: PMC3023626          DOI: 10.4161/chim.1.2.13770

Source DB:  PubMed          Journal:  Chimerism        ISSN: 1938-1964


  14 in total

1.  Creation of a double chimera after the transplantation of umbilical-cord blood from two partially matched unrelated donors.

Authors:  J N Barker; D J Weisdorf; J E Wagner
Journal:  N Engl J Med       Date:  2001-06-14       Impact factor: 91.245

2.  Long-term mixed full-donor chimerism with dominance reversion after a double-unit cord blood transplant.

Authors:  Hsiu-Ju Yen; Tzeon-Jye Chiou; Giun-Yi Hung; Chia-Yau Chang; Ming-Yun Hsieh; Cheng-Hwai Tzeng; Po-Min Chen; Ren-Bin Tang
Journal:  Eur J Haematol       Date:  2008-01-14       Impact factor: 2.997

3.  Double-chimaerism after transplantation of two human leucocyte antigen mismatched, unrelated cord blood units.

Authors:  Marcos De Lima; Lisa S St John; Eric D Wieder; Ming S Lee; John McMannis; Safa Karandish; Sergio Giralt; Miroslav Beran; Daniel Couriel; Martin Korbling; Samer Bibawi; Richard Champlin; Krishna V Komanduri
Journal:  Br J Haematol       Date:  2002-12       Impact factor: 6.998

4.  Dose study of thymoglobulin during conditioning for unrelated donor allogeneic stem-cell transplantation.

Authors:  Mats Remberger; Britt-Marie Svahn; Jonas Mattsson; Olle Ringdén
Journal:  Transplantation       Date:  2004-07-15       Impact factor: 4.939

5.  Stable mixed donor-donor chimerism after double cord blood transplantation.

Authors:  Sofia Berglund; Mantas Okas; Jens Gertow; Michael Uhlin; Jonas Mattsson
Journal:  Int J Hematol       Date:  2009-08-22       Impact factor: 2.490

6.  Unrelated cord blood and mismatched unrelated volunteer donor transplants, two alternatives in patients who lack an HLA-identical donor.

Authors:  O Ringdén; M Okas; M Uhlin; M Uzunel; M Remberger; J Mattsson
Journal:  Bone Marrow Transplant       Date:  2008-09-01       Impact factor: 5.483

7.  Relapse risk after umbilical cord blood transplantation: enhanced graft-versus-leukemia effect in recipients of 2 units.

Authors:  Michael R Verneris; Claudio G Brunstein; Juliet Barker; Margaret L MacMillan; Todd DeFor; David H McKenna; Michael J Burke; Bruce R Blazar; Jeffrey S Miller; Philip B McGlave; Daniel J Weisdorf; John E Wagner
Journal:  Blood       Date:  2009-08-25       Impact factor: 22.113

8.  Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplantation outcomes in 110 adults with hematologic disease.

Authors:  Claudio G Brunstein; Juliet N Barker; Daniel J Weisdorf; Todd E DeFor; Jeffrey S Miller; Bruce R Blazar; Philip B McGlave; John E Wagner
Journal:  Blood       Date:  2007-06-14       Impact factor: 22.113

9.  Single-unit dominance after double-unit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit.

Authors:  Jonathan A Gutman; Cameron J Turtle; Thomas J Manley; Shelly Heimfeld; Irwin D Bernstein; Stanley R Riddell; Colleen Delaney
Journal:  Blood       Date:  2009-10-12       Impact factor: 22.113

10.  KIR-ligand incompatibility in the graft-versus-host direction improves outcomes after umbilical cord blood transplantation for acute leukemia.

Authors:  R Willemze; C A Rodrigues; M Labopin; G Sanz; G Michel; G Socié; B Rio; A Sirvent; M Renaud; L Madero; M Mohty; C Ferra; F Garnier; P Loiseau; J Garcia; L Lecchi; G Kögler; Y Beguin; C Navarrete; T Devos; I Ionescu; K Boudjedir; A-L Herr; E Gluckman; V Rocha
Journal:  Leukemia       Date:  2009-01-08       Impact factor: 11.528

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