Literature DB >> 21326895

Illuminating transcription pathways using fluorescent reporter genes and yeast functional genomics.

Pinay Kainth1, Brenda Andrews.   

Abstract

Technological advances have enabled researchers to probe gene regulatory pathways on an unprecedented scale. Here, we summarize our recent work that exploits a systematic screening approach in the budding yeast to discover regulators of a promoter of interest. We discuss future applications of our approach based on emerging themes in the literature.

Entities:  

Keywords:  Saccharomyces cerevisiae; gene expression; reporter gene; reporter screens; synthetic genetic array analysis

Mesh：

Substances：

Year:  2010        PMID： 21326895      PMCID： PMC3023632          DOI： 10.4161/trns.1.2.12328

Source DB:  PubMed          Journal:  Transcription        ISSN： 2154-1272


  43 in total

1.  The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

Authors:  Philippe Prochasson; Laurence Florens; Selene K Swanson; Michael P Washburn; Jerry L Workman
Journal:  Genes Dev       Date:  2005-11-01       Impact factor: 11.361

2.  The synthetic genetic interaction spectrum of essential genes.

Authors:  Armaity P Davierwala; Jennifer Haynes; Zhijian Li; Renée L Brost; Mark D Robinson; Lisa Yu; Sanie Mnaimneh; Huiming Ding; Hongwei Zhu; Yiqun Chen; Xin Cheng; Grant W Brown; Charles Boone; Brenda J Andrews; Timothy R Hughes
Journal:  Nat Genet       Date:  2005-09-11       Impact factor: 38.330

Review 3.  Regulation of histone synthesis and nucleosome assembly.

Authors:  Akash Gunjan; Johanna Paik; Alain Verreault
Journal:  Biochimie       Date:  2005-03-17       Impact factor: 4.079

Review 4.  Histone chaperones: an escort network regulating histone traffic.

Authors:  Leanne De Koning; Armelle Corpet; James E Haber; Geneviève Almouzni
Journal:  Nat Struct Mol Biol       Date:  2007-11-05       Impact factor: 15.369

5.  Quantitative phenotyping via deep barcode sequencing.

Authors:  Andrew M Smith; Lawrence E Heisler; Joseph Mellor; Fiona Kaper; Michael J Thompson; Mark Chee; Frederick P Roth; Guri Giaever; Corey Nislow
Journal:  Genome Res       Date:  2009-07-21       Impact factor: 9.043

6.  Trans-acting regulatory mutations that alter transcription of Saccharomyces cerevisiae histone genes.

Authors:  M A Osley; D Lycan
Journal:  Mol Cell Biol       Date:  1987-12       Impact factor: 4.272

7.  Cell-cycle regulation of yeast histone mRNA.

Authors:  L M Hereford; M A Osley; T R Ludwig; C S McLaughlin
Journal:  Cell       Date:  1981-05       Impact factor: 41.582

8.  Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes.

Authors:  Adam Siepel; Gill Bejerano; Jakob S Pedersen; Angie S Hinrichs; Minmei Hou; Kate Rosenbloom; Hiram Clawson; John Spieth; Ladeana W Hillier; Stephen Richards; George M Weinstock; Richard K Wilson; Richard A Gibbs; W James Kent; Webb Miller; David Haussler
Journal:  Genome Res       Date:  2005-07-15       Impact factor: 9.043

9.  Genetic analysis of genome-wide variation in human gene expression.

Authors:  Michael Morley; Cliona M Molony; Teresa M Weber; James L Devlin; Kathryn G Ewens; Richard S Spielman; Vivian G Cheung
Journal:  Nature       Date:  2004-07-21       Impact factor: 49.962

10.  Comprehensive genetic analysis of transcription factor pathways using a dual reporter gene system in budding yeast.

Authors:  Pinay Kainth; Holly Elizabeth Sassi; Lourdes Peña-Castillo; Gordon Chua; Timothy R Hughes; Brenda Andrews
Journal:  Methods       Date:  2009-03-06       Impact factor: 3.608
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  2 in total

1.  Beyond Agar: Gel Substrates with Improved Optical Clarity and Drug Efficiency and Reduced Autofluorescence for Microbial Growth Experiments.

Authors:  Philipp A Jaeger; Cameron McElfresh; Lily R Wong; Trey Ideker
Journal:  Appl Environ Microbiol       Date:  2015-06-12       Impact factor: 4.792

2.  Rapid identification of mRNA processing defects with a novel single-cell yeast reporter.

Authors:  Matthew R Sorenson; Scott W Stevens
Journal:  RNA       Date:  2014-03-26       Impact factor: 4.942
  2 in total

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