Literature DB >> 21326199

HTRA proteases: regulated proteolysis in protein quality control.

Tim Clausen1, Markus Kaiser, Robert Huber, Michael Ehrmann.   

Abstract

Controlled proteolysis underlies a vast diversity of protective and regulatory processes that are of key importance to cell fate. The unique molecular architecture of the widely conserved high temperature requirement A (HTRA) proteases has evolved to mediate critical aspects of ATP-independent protein quality control. The simple combination of a classic Ser protease domain and a carboxy-terminal peptide-binding domain produces cellular factors of remarkable structural and functional plasticity that allow cells to rapidly respond to the presence of misfolded or mislocalized polypeptides.

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Year:  2011        PMID： 21326199     DOI： 10.1038/nrm3065

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  99 in total

1.  Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation.

Authors:  Rainer Friedrich; Peter Panizzi; Pablo Fuentes-Prior; Klaus Richter; Ingrid Verhamme; Patricia J Anderson; Shun-Ichiro Kawabata; Robert Huber; Wolfram Bode; Paul E Bock
Journal:  Nature       Date:  2003-10-02       Impact factor: 49.962

Review 2.  Structural and mechanistic insight into how antibodies inhibit serine proteases.

Authors:  Rajkumar Ganesan; Charles Eigenbrot; Daniel Kirchhofer
Journal:  Biochem J       Date:  2010-09-01       Impact factor: 3.857

3.  HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues.

Authors:  Tobias Krojer; Justyna Sawa; Robert Huber; Tim Clausen
Journal:  Nat Struct Mol Biol       Date:  2010-06-27       Impact factor: 15.369

4.  The thylakoid protease Deg1 is involved in photosystem-II assembly in Arabidopsis thaliana.

Authors:  Xuwu Sun; Min Ouyang; Jinkui Guo; Jinfang Ma; Congming Lu; Zach Adam; Lixin Zhang
Journal:  Plant J       Date:  2010-01-18       Impact factor: 6.417

5.  Role of DegP for two-partner secretion in Bordetella.

Authors:  C Baud; H Hodak; E Willery; H Drobecq; C Locht; M Jamin; F Jacob-Dubuisson
Journal:  Mol Microbiol       Date:  2009-08-24       Impact factor: 3.501

6.  New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays.

Authors:  Jonathan B Baell; Georgina A Holloway
Journal:  J Med Chem       Date:  2010-04-08       Impact factor: 7.446

Review 7.  High-temperature requirement factor A3 (Htra3): a novel serine protease and its potential role in ovarian function and ovarian cancers.

Authors:  Marissa A Bowden; Ann E Drummond; Peter J Fuller; Lois A Salamonsen; Jock K Findlay; Guiying Nie
Journal:  Mol Cell Endocrinol       Date:  2010-06-09       Impact factor: 4.102

8.  Implications of the serine protease HtrA1 in amyloid precursor protein processing.

Authors:  Sandra Grau; Alfonso Baldi; Rossana Bussani; Xiaodan Tian; Raluca Stefanescu; Michael Przybylski; Peter Richards; Simon A Jones; Viji Shridhar; Tim Clausen; Michael Ehrmann
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-26       Impact factor: 11.205

9.  The stromal chloroplast Deg7 protease participates in the repair of photosystem II after photoinhibition in Arabidopsis.

Authors:  Xuwu Sun; Tingjiao Fu; Ning Chen; Jinkui Guo; Jinfang Ma; Meijuan Zou; Congming Lu; Lixin Zhang
Journal:  Plant Physiol       Date:  2010-01-20       Impact factor: 8.340

10.  Activation of DegP chaperone-protease via formation of large cage-like oligomers upon binding to substrate proteins.

Authors:  Jiansen Jiang; Xuefeng Zhang; Yong Chen; Yi Wu; Z Hong Zhou; Zengyi Chang; Sen-Fang Sui
Journal:  Proc Natl Acad Sci U S A       Date:  2008-08-12       Impact factor: 11.205
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  180 in total

1.  The crystal structure of Mycobacterium tuberculosis high-temperature requirement A protein reveals an autoregulatory mechanism.

Authors:  Arvind Kumar Gupta; Debashree Behera; Balasubramanian Gopal
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2018-11-29       Impact factor: 1.056

2.  Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival.

Authors:  Seokhee Kim; Robert T Sauer
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-23       Impact factor: 11.205

Review 3.  Membrane proteases in the bacterial protein secretion and quality control pathway.

Authors:  Ross E Dalbey; Peng Wang; Jan Maarten van Dijl
Journal:  Microbiol Mol Biol Rev       Date:  2012-06       Impact factor: 11.056

4.  Borrelia burgdorferi HtrA: evidence for twofold proteolysis of outer membrane protein p66.

Authors:  James L Coleman; Alvaro Toledo; Jorge L Benach
Journal:  Mol Microbiol       Date:  2015-10-20       Impact factor: 3.501

5.  The unique trimeric assembly of the virulence factor HtrA from Helicobacter pylori occurs via N-terminal domain swapping.

Authors:  Zhemin Zhang; Qi Huang; Xuan Tao; Guobing Song; Peng Zheng; Hongyan Li; Hongzhe Sun; Wei Xia
Journal:  J Biol Chem       Date:  2019-04-01       Impact factor: 5.157

6.  Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates.

Authors:  Annette Tennstaedt; Simon Pöpsel; Linda Truebestein; Patrick Hauske; Anke Brockmann; Nina Schmidt; Inga Irle; Barbara Sacca; Christof M Niemeyer; Roland Brandt; Hanna Ksiezak-Reding; Anca Laura Tirniceriu; Rupert Egensperger; Alfonso Baldi; Leif Dehmelt; Markus Kaiser; Robert Huber; Tim Clausen; Michael Ehrmann
Journal:  J Biol Chem       Date:  2012-04-25       Impact factor: 5.157

Review 7.  Mitochondrial protein quality control in health and disease.

Authors:  Michael J Baker; Catherine S Palmer; Diana Stojanovski
Journal:  Br J Pharmacol       Date:  2014-04       Impact factor: 8.739

8.  BMP-2, hypoxia, and COL1A1/HtrA1 siRNAs favor neo-cartilage hyaline matrix formation in chondrocytes.

Authors:  David Ollitrault; Florence Legendre; Carole Drougard; Mélanie Briand; Hervé Benateau; Didier Goux; Hanane Chajra; Laurent Poulain; Daniel Hartmann; Denis Vivien; Vijayalakshmi Shridhar; Alfonso Baldi; Frédéric Mallein-Gerin; Karim Boumediene; Magali Demoor; Philippe Galera
Journal:  Tissue Eng Part C Methods       Date:  2014-07-31       Impact factor: 3.056

Review 9.  Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's disease.

Authors:  Georgia S Gaki; Athanasios G Papavassiliou
Journal:  Neuromolecular Med       Date:  2014-02-13       Impact factor: 3.843

10.  Structural insight into magnetochrome-mediated magnetite biomineralization.

Authors:  Marina I Siponen; Pierre Legrand; Marc Widdrat; Stephanie R Jones; Wei-Jia Zhang; Michelle C Y Chang; Damien Faivre; Pascal Arnoux; David Pignol
Journal:  Nature       Date:  2013-10-06       Impact factor: 49.962
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