Literature DB >> 21325894

The integral role of mTOR in lipid metabolism.

Ghada A Soliman.   

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Year:  2011        PMID： 21325894      PMCID： PMC3100868          DOI： 10.4161/cc.10.6.14930

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  16 in total

1.  Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration.

Authors:  Pazit Polak; Nadine Cybulski; Jerome N Feige; Johan Auwerx; Markus A Rüegg; Michael N Hall
Journal:  Cell Metab       Date:  2008-11       Impact factor: 27.287

2.  mTORC1 inhibition via rapamycin promotes triacylglycerol lipolysis and release of free fatty acids in 3T3-L1 adipocytes.

Authors:  Ghada A Soliman; Hugo A Acosta-Jaquez; Diane C Fingar
Journal:  Lipids       Date:  2010-11-02       Impact factor: 1.880

3.  Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.

Authors:  Olivier Le Bacquer; Emmanuel Petroulakis; Sabina Paglialunga; Francis Poulin; Denis Richard; Katherine Cianflone; Nahum Sonenberg
Journal:  J Clin Invest       Date:  2007-02       Impact factor: 14.808

4.  regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis.

Authors:  Jae Eun Kim; Jie Chen
Journal:  Diabetes       Date:  2004-11       Impact factor: 9.461

Review 5.  mTOR: from growth signal integration to cancer, diabetes and ageing.

Authors:  Roberto Zoncu; Alejo Efeyan; David M Sabatini
Journal:  Nat Rev Mol Cell Biol       Date:  2010-12-15       Impact factor: 94.444

6.  S6K1 plays a critical role in early adipocyte differentiation.

Authors:  Larissa S Carnevalli; Kouhei Masuda; Francesca Frigerio; Olivier Le Bacquer; Sung Hee Um; Valentina Gandin; Ivan Topisirovic; Nahum Sonenberg; George Thomas; Sara C Kozma
Journal:  Dev Cell       Date:  2010-05-18       Impact factor: 12.270

7.  The mammalian target of rapamycin regulates lipid metabolism in primary cultures of rat hepatocytes.

Authors:  Nicholas F Brown; Maja Stefanovic-Racic; Ian J Sipula; German Perdomo
Journal:  Metabolism       Date:  2007-11       Impact factor: 8.694

8.  Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism.

Authors:  Anil Kumar; John C Lawrence; Dae Young Jung; Hwi Jin Ko; Susanna R Keller; Jason K Kim; Mark A Magnuson; Thurl E Harris
Journal:  Diabetes       Date:  2010-03-23       Impact factor: 9.461

9.  The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation.

Authors:  Tao Peng; Todd R Golub; David M Sabatini
Journal:  Mol Cell Biol       Date:  2002-08       Impact factor: 4.272

10.  Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1.

Authors:  Kevin T Jones; Elisabeth R Greer; David Pearce; Kaveh Ashrafi
Journal:  PLoS Biol       Date:  2009-03-03       Impact factor: 8.029
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  29 in total

1.  The butterfly effect in cancer: a single base mutation can remodel the cell.

Authors:  Jonathan R Hart; Yaoyang Zhang; Lujian Liao; Lynn Ueno; Lisa Du; Marloes Jonkers; John R Yates; Peter K Vogt
Journal:  Proc Natl Acad Sci U S A       Date:  2015-01-12       Impact factor: 11.205

2.  Effects of Metformin and a Mammalian Target of Rapamycin (mTOR) ATP-Competitive Inhibitor on Targeted Metabolomics in Pancreatic Cancer Cell Line.

Authors:  Ghada A Soliman; Sharalyn M Steenson; Asserewou H Etekpo
Journal:  Metabolomics (Los Angel)       Date:  2016-08-20

3.  Rapamycin increases mitochondrial efficiency by mtDNA-dependent reprogramming of mitochondrial metabolism in Drosophila.

Authors:  Eugenia Villa-Cuesta; Marissa A Holmbeck; David M Rand
Journal:  J Cell Sci       Date:  2014-03-07       Impact factor: 5.285

4.  MSK1-Mediated β-Catenin Phosphorylation Confers Resistance to PI3K/mTOR Inhibitors in Glioblastoma.

Authors:  Shaofang Wu; Shuzhen Wang; Siyuan Zheng; Roel Verhaak; Dimpy Koul; W K Alfred Yung
Journal:  Mol Cancer Ther       Date:  2016-04-22       Impact factor: 6.261

5.  Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1.

Authors:  Meilian Liu; Juli Bai; Sijia He; Ricardo Villarreal; Derong Hu; Chuntao Zhang; Xin Yang; Huiyun Liang; Thomas J Slaga; Yonghao Yu; Zhiguang Zhou; John Blenis; Philipp E Scherer; Lily Q Dong; Feng Liu
Journal:  Cell Metab       Date:  2014-04-17       Impact factor: 27.287

6.  Inhibition of protein arginine methyltransferase 5 enhances hepatic mitochondrial biogenesis.

Authors:  Lei Huang; Jehnan Liu; Xiao-Ou Zhang; Katelyn Sibley; Sonia M Najjar; Mary M Lee; Qiong Wu
Journal:  J Biol Chem       Date:  2018-05-17       Impact factor: 5.157

7.  Vitamin C inhibits lipid deposition through GSK-3β/mTOR signaling in the liver of zebrafish.

Authors:  Dongwu Liu; Yaqi Gu; Qiuxiang Pang; Qiang Han; Ao Li; Weiwei Wu; Xiuzhen Zhang; Qilong Shi; Lanlan Zhu; Hairui Yu; Qin Zhang
Journal:  Fish Physiol Biochem       Date:  2019-11-28       Impact factor: 2.794

8.  Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice.

Authors:  Zhenjiang Liu; Lu Gan; Guannv Liu; Yizhe Chen; Tianjiao Wu; Fei Feng; Chao Sun
Journal:  J Lipid Res       Date:  2016-06-17       Impact factor: 5.922

Review 9.  Tumor suppressor p53 and its mutants in cancer metabolism.

Authors:  Juan Liu; Cen Zhang; Wenwei Hu; Zhaohui Feng
Journal:  Cancer Lett       Date:  2013-12-24       Impact factor: 8.679

Review 10.  Potential therapeutic effects of mTOR inhibition in atherosclerosis.

Authors:  Ammar Kurdi; Guido R Y De Meyer; Wim Martinet
Journal:  Br J Clin Pharmacol       Date:  2015-12-29       Impact factor: 4.335
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