OBJECTIVE: To summarize the indications and techniques for parathyroid autotransplantation and to explore other aspects of the field that warrant further research and discussion. METHODS: Review of relevant literature with focus on parathyroid autotransplantation and cryopreservation. RESULTS: Parathyroid autotransplantation is an important technique used by surgeons to circumvent postoperative hypoparathyroidism. Immediate autotransplantation is used intraoperatively, most commonly in the setting of total thyroidectomy or during total parathyroidectomy in a patient with parathyroid hyperplasia. Delayed autotransplantation with cryopreservation is typically used in patients with persistent or recurrent hyperparathyroidism who require repeated cervical exploration. CONCLUSIONS: The success rate of autotransplantation in preventing postoperative hypoparathyroidism reported in the literature is highly variable and is dependent on timing, disease, and duration of tissue storage. Ultimately, surgical planning for patients with hyperparathyroidism involves finding a balance between decreasing a patient's symptoms, increasing the time of eucalcemia, and avoiding the complications of permanent hypoparathyroidism.
OBJECTIVE: To summarize the indications and techniques for parathyroid autotransplantation and to explore other aspects of the field that warrant further research and discussion. METHODS: Review of relevant literature with focus on parathyroid autotransplantation and cryopreservation. RESULTS: Parathyroid autotransplantation is an important technique used by surgeons to circumvent postoperative hypoparathyroidism. Immediate autotransplantation is used intraoperatively, most commonly in the setting of total thyroidectomy or during total parathyroidectomy in a patient with parathyroid hyperplasia. Delayed autotransplantation with cryopreservation is typically used in patients with persistent or recurrent hyperparathyroidism who require repeated cervical exploration. CONCLUSIONS: The success rate of autotransplantation in preventing postoperative hypoparathyroidism reported in the literature is highly variable and is dependent on timing, disease, and duration of tissue storage. Ultimately, surgical planning for patients with hyperparathyroidism involves finding a balance between decreasing a patient's symptoms, increasing the time of eucalcemia, and avoiding the complications of permanent hypoparathyroidism.
Authors: Hae Sang Park; Soo Yeon Jung; Ha Young Kim; Da Yeon Kim; Moon Suk Kim; Sung Min Chung; Young-Soo Rho; Han Su Kim Journal: Eur Arch Otorhinolaryngol Date: 2014-09-03 Impact factor: 2.503
Authors: Sahzene Yavuz; William F Simonds; Lee S Weinstein; Michael T Collins; Electron Kebebew; Naris Nilubol; Giao Q Phan; Steven K Libutti; Alan T Remaley; Manuel Van Deventer; Stephen J Marx Journal: J Clin Endocrinol Metab Date: 2012-04-16 Impact factor: 5.958
Authors: Hae Sang Park; Soo Yeon Jung; Ha Yeong Kim; Du Young Ko; Sung Min Chung; Byeongmoon Jeong; Han Su Kim Journal: Eur Arch Otorhinolaryngol Date: 2016-03-19 Impact factor: 2.503
Authors: Natalie E Cusano; Laura Anderson; Mishaela R Rubin; Barbara C Silva; Aline G Costa; Dinaz Irani; James Sliney; John P Bilezikian Journal: J Clin Endocrinol Metab Date: 2013-09-13 Impact factor: 5.958