Literature DB >> 21324798

The role of plastic surgery in sarcoma treatment.

Juan María Viñls Viñals1, Diana Pérez Sidelnikova, José María Serra Payro, José Antonio Palacín Porte, Anna Belén López Ojeda, Mari Carmen Higueras Suñe, Javier García del Muro, Alicia Lozano Borbalas, Frederic Portabella Blavia, Francisco Javier Sanjuán Garriga, José Antonio Narváez García.   

Abstract

INTRODUCTION: Sarcomas are low-incidence tumours, but their poor prognosis and complex treatment require the work of a multidisciplinary medical team. The Plastic Surgery Service forms part of the Sarcoma Functional Unit in our centre, performing tumour exeresis as well as immediate reconstruction.
MATERIALS AND METHODS: We present a retrospective study on the experience of the Plastic Surgery Service of the Hospital Universitario de Bellvitge in the treatment of 133 sarcomas over 20 years.
RESULTS: The surgical treatment was based on local radical surgery supported by primary reconstructive surgery in 42.9% of the cases, with an amputation rate in limb sarcomas of 9.7%. Radiotherapy and chemotherapy were used in the high-grade sarcomas as adjuvant treatment. The anatomical location of the head and neck was associated with the need for reconstructive procedures. Survival free from local recurrence was 84.72% at 5 years. Disease-specific survival was 81.22% at 5 years. The only prognostic factor for survival in our series was histological grade.
CONCLUSIONS: Primary reconstructive surgery has a fundamental role in sarcoma treatment enabling radical surgical resection, avoiding amputations and facilitating adjuvant treatments.

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Year:  2011        PMID: 21324798     DOI: 10.1007/s12094-011-0626-9

Source DB:  PubMed          Journal:  Clin Transl Oncol        ISSN: 1699-048X            Impact factor:   3.405


  22 in total

1.  The principles and technique of resection of soft parts for sarcoma. 1958.

Authors:  Lemuel Bowden; Robert J Booher
Journal:  Clin Orthop Relat Res       Date:  2004-09       Impact factor: 4.176

Review 2.  Evidence-based recommendations for local therapy for soft tissue sarcomas.

Authors:  Peter W T Pisters; Brian O'Sullivan; Robert G Maki
Journal:  J Clin Oncol       Date:  2007-03-10       Impact factor: 44.544

3.  Adjuvant chemotherapy for adult soft tissue sarcomas of the extremities and girdles: results of the Italian randomized cooperative trial.

Authors:  S Frustaci; F Gherlinzoni; A De Paoli; M Bonetti; A Azzarelli; A Comandone; P Olmi; A Buonadonna; G Pignatti; E Barbieri; G Apice; H Zmerly; D Serraino; P Picci
Journal:  J Clin Oncol       Date:  2001-03-01       Impact factor: 44.544

4.  Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities.

Authors:  P W Pisters; D H Leung; J Woodruff; W Shi; M F Brennan
Journal:  J Clin Oncol       Date:  1996-05       Impact factor: 44.544

5.  Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma.

Authors:  P W Pisters; L B Harrison; D H Leung; J M Woodruff; E S Casper; M F Brennan
Journal:  J Clin Oncol       Date:  1996-03       Impact factor: 44.544

6.  Prognostic factors for survival in patients with locally recurrent extremity soft tissue sarcomas.

Authors:  Fritz C Eilber; Murray F Brennan; Elyn Riedel; Kaled M Alektiar; Cristina R Antonescu; Samuel Singer
Journal:  Ann Surg Oncol       Date:  2005-03-03       Impact factor: 5.344

7.  The indications for and the prognostic significance of amputation as the primary surgical procedure for localized soft tissue sarcoma of the extremity.

Authors:  Michelle A Ghert; Adesegun Abudu; Natasha Driver; Aileen M Davis; Anthony M Griffin; Dawn Pearce; Lawrence White; Brian O'Sullivan; Charles N Catton; Robert S Bell; Jay S Wunder
Journal:  Ann Surg Oncol       Date:  2004-12-27       Impact factor: 5.344

8.  Relationship between surgical margins and local recurrence in sarcomas of the spine.

Authors:  Robert Talac; Michael J Yaszemski; Bradford L Currier; Bruno Fuchs; Mark B Dekutoski; Choll W Kim; Franklin H Sim
Journal:  Clin Orthop Relat Res       Date:  2002-04       Impact factor: 4.176

Review 9.  Predictive variables detailing the recurrence rate of soft tissue sarcomas.

Authors:  Stephen R Grobmyer; Murray F Brennan
Journal:  Curr Opin Oncol       Date:  2003-07       Impact factor: 3.645

10.  Conservative surgery and adjuvant radiation therapy in the management of adult soft tissue sarcoma of the extremities: clinical and radiobiological results.

Authors:  A J Mundt; A Awan; G S Sibley; M Simon; S J Rubin; B Samuels; W Wong; M Beckett; S Vijayakumar; R R Weichselbaum
Journal:  Int J Radiat Oncol Biol Phys       Date:  1995-07-15       Impact factor: 7.038

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  1 in total

1.  Clinical practice guidelines for the diagnosis and treatment of patients with soft tissue sarcoma by the Spanish group for research in sarcomas (GEIS).

Authors:  Xavier Garcia del Muro; Enrique de Alava; Vicenç Artigas; Silvia Bague; Alejandro Braña; Ricardo Cubedo; Josefina Cruz; Nuria Mulet-Margalef; Jose A Narvaez; Oscar Martinez Tirado; Claudia Valverde; Ramona Verges; Joan Viñals; Javier Martin-Broto
Journal:  Cancer Chemother Pharmacol       Date:  2015-11-12       Impact factor: 3.333

  1 in total

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