Literature DB >> 21324795

Monoclonal antibodies for medical oncology: a few critical perspectives.

Cristóbal Belda-Iniesta1, Inmaculada Ibáñez de Cáceres, Javier de Castro.   

Abstract

Incorporation of antibodies as weapons for cancer therapy has meant a turning point in the survival, clinical and radiological response of many oncology patients. These drugs are effective, well designed missiles that either alone or in combination with chemotherapy are unavoidable weapons for breast, lung and colon cancer as well as for haematological tumours. In addition, incoming monoclonal antibodies (mAbs) and folder-like proteins will be incorporated into clinical practice in the near future. This review aims to discuss a few imminent indications of current mAbs that are used for solid tumours and to briefly introduce future mAbs to the reader.

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Year:  2011        PMID: 21324795     DOI: 10.1007/s12094-011-0623-z

Source DB:  PubMed          Journal:  Clin Transl Oncol        ISSN: 1699-048X            Impact factor:   3.405


  12 in total

1.  Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial.

Authors:  Yung-Jue Bang; Eric Van Cutsem; Andrea Feyereislova; Hyun C Chung; Lin Shen; Akira Sawaki; Florian Lordick; Atsushi Ohtsu; Yasushi Omuro; Taroh Satoh; Giuseppe Aprile; Evgeny Kulikov; Julie Hill; Michaela Lehle; Josef Rüschoff; Yoon-Koo Kang
Journal:  Lancet       Date:  2010-08-19       Impact factor: 79.321

Review 2.  Bisphosphonates and RANK ligand inhibitors for the treatment and prevention of metastatic bone disease.

Authors:  H L Neville-Webbe; R E Coleman
Journal:  Eur J Cancer       Date:  2010-03-27       Impact factor: 9.162

Review 3.  Panitumumab: a review of its use in metastatic colorectal cancer.

Authors:  Gillian M Keating
Journal:  Drugs       Date:  2010-05-28       Impact factor: 9.546

Review 4.  Chemotherapy for advanced gastric cancer.

Authors:  A D Wagner; W Grothe; S Behl; G Kleber; A Grothey; J Haerting; W E Fleig
Journal:  Cochrane Database Syst Rev       Date:  2005-04-18

Review 5.  HER2 and hormone receptor-positive breast cancer--blocking the right target.

Authors:  Javier Cortés; Cristina Saura; Meritxell Bellet; Eva Muñoz-Couselo; Natalia Ramírez-Merino; Virginia Calvo; Jose Pérez; María Vidal
Journal:  Nat Rev Clin Oncol       Date:  2010-12-14       Impact factor: 66.675

6.  Prospective randomized trial comparing mitomycin, cisplatin, and protracted venous-infusion fluorouracil (PVI 5-FU) With epirubicin, cisplatin, and PVI 5-FU in advanced esophagogastric cancer.

Authors:  P Ross; M Nicolson; D Cunningham; J Valle; M Seymour; P Harper; T Price; H Anderson; T Iveson; T Hickish; F Lofts; A Norman
Journal:  J Clin Oncol       Date:  2002-04-15       Impact factor: 44.544

7.  The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial.

Authors:  Markus M Heiss; Pawel Murawa; Piotr Koralewski; Elzbieta Kutarska; Olena O Kolesnik; Vladimir V Ivanchenko; Alexander S Dudnichenko; Birute Aleknaviciene; Arturas Razbadauskas; Martin Gore; Elena Ganea-Motan; Tudor Ciuleanu; Pauline Wimberger; Alexander Schmittel; Barbara Schmalfeldt; Alexander Burges; Carsten Bokemeyer; Horst Lindhofer; Angelika Lahr; Simon L Parsons
Journal:  Int J Cancer       Date:  2010-11-01       Impact factor: 7.396

8.  PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer.

Authors:  Fotios Loupakis; Luca Pollina; Irene Stasi; Annamaria Ruzzo; Mario Scartozzi; Daniele Santini; Gianluca Masi; Francesco Graziano; Chiara Cremolini; Eliana Rulli; Emanuele Canestrari; Niccola Funel; Gaia Schiavon; Iacopo Petrini; Mauro Magnani; Giuseppe Tonini; Daniela Campani; Irene Floriani; Stefano Cascinu; Alfredo Falcone
Journal:  J Clin Oncol       Date:  2009-04-27       Impact factor: 44.544

9.  Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer.

Authors:  Giorgio Vittorio Scagliotti; Purvish Parikh; Joachim von Pawel; Bonne Biesma; Johan Vansteenkiste; Christian Manegold; Piotr Serwatowski; Ulrich Gatzemeier; Raghunadharao Digumarti; Mauro Zukin; Jin S Lee; Anders Mellemgaard; Keunchil Park; Shehkar Patil; Janusz Rolski; Tuncay Goksel; Filippo de Marinis; Lorinda Simms; Katherine P Sugarman; David Gandara
Journal:  J Clin Oncol       Date:  2008-05-27       Impact factor: 44.544

10.  Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial.

Authors:  Robert Pirker; Jose R Pereira; Aleksandra Szczesna; Joachim von Pawel; Maciej Krzakowski; Rodryg Ramlau; Ihor Vynnychenko; Keunchil Park; Chih-Teng Yu; Valentyn Ganul; Jae-Kyung Roh; Emilio Bajetta; Kenneth O'Byrne; Filippo de Marinis; Wilfried Eberhardt; Thomas Goddemeier; Michael Emig; Ulrich Gatzemeier
Journal:  Lancet       Date:  2009-05-02       Impact factor: 79.321

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  2 in total

Review 1.  Pretargeting: taking an alternate route for localizing radionuclides.

Authors:  Robert M Sharkey; Chien-Hsing Chang; Edmund A Rossi; William J McBride; David M Goldenberg
Journal:  Tumour Biol       Date:  2012-03-07

2.  Anti-cadherin-17 antibody modulates beta-catenin signaling and tumorigenicity of hepatocellular carcinoma.

Authors:  Yonggang Wang; Felix H Shek; Kwong F Wong; Ling Xiao Liu; Xiao Qian Zhang; Yi Yuan; Ester Khin; Mei-Yu Hu; Jian Hua Wang; Ronnie T P Poon; Wanjin Hong; Nikki P Lee; John M Luk
Journal:  PLoS One       Date:  2013-09-11       Impact factor: 3.240

  2 in total

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