| Literature DB >> 21324690 |
Eiji Nakata1, Yoshijiro Nazumi, Yoshihiro Yukimachi, Yoshihiro Uto, Hiroshi Maezawa, Toshihiro Hashimoto, Yasuko Okamoto, Hitoshi Hori.
Abstract
We report the synthesis and properties of two new seminaphthorhodafluor (SNARF) derivatives, SNARF-F and SNARF-Cl. Both these derivatives exhibit typical red shifts of absorption and fluorescence, and higher cell permeability as compared to traditional SNARF, while the pH-dependent dual-emission characteristics are well retained. In particular, the lower pK(a) (7.38) of SNARF-F makes it more suitable than traditional SNARF derivatives for intracellular applications.Mesh：
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Year: 2011 PMID： 21324690 DOI： 10.1016/j.bmcl.2011.01.105
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823