Literature DB >> 21324448

Impact of submucous myoma on the severity of anemia.

Jehn-Hsiahn Yang1, Mei-Jou Chen, Chin-Der Chen, Chi-Ling Chen, Hong-Nerng Ho, Yu-Shih Yang.   

Abstract

OBJECTIVE: To analyze the impact of the diameter (myoma-φ) and the uterine cavity protruding proportion (protruding %) of the submucous myoma on serum hemoglobin (Hb) level.
DESIGN: Retrospective descriptive study.
SETTING: Tertiary university hospital. PATIENT(S): Two hundred fifty-nine women with a single submucous myoma. INTERVENTION(S): Transvaginal ultrasound examination and office hysteroscopy. MAIN OUTCOME MEASURE(S): Myoma-φ and protruding % were determined with transvaginal ultrasound scan and office hysteroscopy. Menorrhagic period (months) and serum Hb were recorded within 2 weeks of these examinations. RESULT(S): Serum Hb negatively correlated with myoma-φ, protruding %, and menorrhagic period. The negative association between serum Hb and protruding % was even more prominent after adjusting for myoma-φ. Multivariate regression analysis revealed that myoma-φ and protruding %, after adjusting for the confounding effect of menorrhagic period, maintained a strongly negative correlation with serum Hb level. When myoma-φ was <2 cm, however, the serum Hb levels were similar regardless of the protruding %. CONCLUSION(S): For women with a single submucous myoma, myoma-φ and protruding % can determine the serum Hb level significantly . As myoma-φ and protruding % increased, the serum Hb level decreased accordingly.
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21324448     DOI: 10.1016/j.fertnstert.2011.01.142

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


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