Literature DB >> 21323110

Structural design and experimental analysis of a selective laser sintering system with nano-hydroxyapatite powder.

Cijun Shuai1, Chengde Gao, Yi Nie, Huanglong Hu, Hongyi Qu, Shuping Peng.   

Abstract

Hydroxyapatite (HA) is a ceramic transposition material which has been widely used for artificial bone. However, its applications are limited to a small implantation for non-bearing bone repair due to its high brittleness, low strength and poor mechanical properties. Thus, nanotechnology has been employed to improve the mechanical properties (torsion modulus, tensile strength and fatigue resistance, etc.) of HA for bone implantation. In this study, we developed a selective laser sintering system for fabrication of artificial bone with nano-HA powder. The key characteristics of this novel system is the laser with fast heating and fast cooling properties, which efficiently prevents the nanosize particles from forming micron size ones in the process of the sintering. The microstructure of the sintered nano-HA scaffolds produced in this system was investigated under Scanning Electron Microscopy (SEM). We showed that the size of nano particles were increased with the prolonged sintering time. Moreover, they are more in shape of granules instead of the original shape of needle. We suggest that the nano HA scaffolds which meet the requirements for the mechanical and biological properties of bone can be obtained by optimizing the sintering time.

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Year:  2010        PMID: 21323110     DOI: 10.1166/jbn.2010.1139

Source DB:  PubMed          Journal:  J Biomed Nanotechnol        ISSN: 1550-7033            Impact factor:   4.099


  7 in total

1.  Hydroxyapatite whisker reinforced 63s glass scaffolds for bone tissue engineering.

Authors:  Cijun Shuai; Yiyuan Cao; Chengde Gao; Pei Feng; Tao Xiao; Shuping Peng
Journal:  Biomed Res Int       Date:  2015-03-04       Impact factor: 3.411

2.  Mechanical reinforcement of diopside bone scaffolds with carbon nanotubes.

Authors:  Cijun Shuai; Tingting Liu; Chengde Gao; Pei Feng; Shuping Peng
Journal:  Int J Mol Sci       Date:  2014-10-23       Impact factor: 5.923

3.  Correlation between properties and microstructure of laser sintered porous β-tricalcium phosphate bone scaffolds.

Authors:  Cijun Shuai; Pei Feng; Liyang Zhang; Chengde Gao; Huanlong Hu; Shuping Peng; Anjie Min
Journal:  Sci Technol Adv Mater       Date:  2013-09-10       Impact factor: 8.090

4.  The Enhancement of Mg Corrosion Resistance by Alloying Mn and Laser-Melting.

Authors:  Youwen Yang; Ping Wu; Qiyuan Wang; Hong Wu; Yong Liu; Youwen Deng; Yuanzhuo Zhou; Cijun Shuai
Journal:  Materials (Basel)       Date:  2016-03-23       Impact factor: 3.623

5.  Enhancement mechanisms of graphene in nano-58S bioactive glass scaffold: mechanical and biological performance.

Authors:  Chengde Gao; Tingting Liu; Cijun Shuai; Shuping Peng
Journal:  Sci Rep       Date:  2014-04-16       Impact factor: 4.379

Review 6.  Current progress in bioactive ceramic scaffolds for bone repair and regeneration.

Authors:  Chengde Gao; Youwen Deng; Pei Feng; Zhongzheng Mao; Pengjian Li; Bo Yang; Junjie Deng; Yiyuan Cao; Cijun Shuai; Shuping Peng
Journal:  Int J Mol Sci       Date:  2014-03-18       Impact factor: 5.923

7.  Synergistic Effect of Carbon Nanotubes and Graphene on Diopside Scaffolds.

Authors:  Tingting Liu; Ping Wu; Chengde Gao; Pei Feng; Tao Xiao; Youwen Deng; Cijun Shuai; Shuping Peng
Journal:  Biomed Res Int       Date:  2016-04-10       Impact factor: 3.411

  7 in total

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