Literature DB >> 21322294

Signalling: REX rules.

Nicola McCarthy.   

Abstract

The RAC-GEF PREX1 integrates signals from tyrosine kinase receptors and GPCRs to activate RAC1.

Entities:  

Year:  2011        PMID： 21322294     DOI： 10.1038/nrc3013

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  2 in total

1.  P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer.

Authors:  J C Montero; S Seoane; A Ocaña; A Pandiella
Journal:  Oncogene       Date:  2010-11-01       Impact factor: 9.867

2.  Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.

Authors:  Maria Soledad Sosa; Cynthia Lopez-Haber; Chengfeng Yang; Hongbin Wang; Mark A Lemmon; John M Busillo; Jiansong Luo; Jeffrey L Benovic; Andres Klein-Szanto; Hiroshi Yagi; J Silvio Gutkind; Ramon E Parsons; Marcelo G Kazanietz
Journal:  Mol Cell       Date:  2010-12-22       Impact factor: 17.970
  2 in total
  3 in total

Review 1.  Genetic predisposition for multiple myeloma.

Authors:  Maroulio Pertesi; Molly Went; Markus Hansson; Kari Hemminki; Richard S Houlston; Björn Nilsson
Journal:  Leukemia       Date:  2020-01-08       Impact factor: 11.528

Review 2.  Regulation and function of P-Rex family Rac-GEFs.

Authors:  Heidi C E Welch
Journal:  Small GTPases       Date:  2015-05-11

3.  Functional dissection of inherited non-coding variation influencing multiple myeloma risk.

Authors:  Ram Ajore; Abhishek Niroula; Maroulio Pertesi; Caterina Cafaro; Malte Thodberg; Molly Went; Erik L Bao; Laura Duran-Lozano; Aitzkoa Lopez de Lapuente Portilla; Thorunn Olafsdottir; Nerea Ugidos-Damboriena; Olafur Magnusson; Mehmet Samur; Caleb A Lareau; Gisli H Halldorsson; Gudmar Thorleifsson; Gudmundur L Norddahl; Kristbjorg Gunnarsdottir; Asta Försti; Hartmut Goldschmidt; Kari Hemminki; Frits van Rhee; Scott Kimber; Adam S Sperling; Martin Kaiser; Kenneth Anderson; Ingileif Jonsdottir; Nikhil Munshi; Thorunn Rafnar; Anders Waage; Niels Weinhold; Unnur Thorsteinsdottir; Vijay G Sankaran; Kari Stefansson; Richard Houlston; Björn Nilsson
Journal:  Nat Commun       Date:  2022-01-10       Impact factor: 17.694
  3 in total

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