Literature DB >> 21320528

The effect of intraperitoneally administered dimethyl sulfoxide on absence-like epileptic activity of freely moving WAG/Rij rats.

Zsolt Kovács1, András Czurkó, Katalin A Kékesi, Gábor Juhász.   

Abstract

Dimethyl sulfoxide (DMSO) is a widely used solvent for water-insoluble molecules and it has antioxidant, neuroprotective and cryopreservative effects. While DMSO is a regularly used solvent in research and a therapeutic agent, several cases of DMSO evoked seizures were reported in the literature. Therefore, we investigated the effect of different doses of DMSO on the absence-like epileptic activity of Wistar Albino Glaxo/Rijswijk (WAG/Rij) rats. We revealed that low doses of DMSO decreased whereas high doses of DMSO increased the absence-like epileptic activity of WAG/Rij rats.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID： 21320528     DOI： 10.1016/j.jneumeth.2011.02.005

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN： 0165-0270            Impact factor:   2.390


  10 in total

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Journal:  J Nat Med       Date:  2021-10-13       Impact factor: 2.343

2.  Lack of evidence for neonatal misoprostol neurodevelopmental toxicity in C57BL6/J mice.

Authors:  Claire M Koenig; Cheryl K Walker; Lihong Qi; Isaac N Pessah; Robert F Berman
Journal:  PLoS One       Date:  2012-06-13       Impact factor: 3.240

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4.  Adenosine A1 Receptor Antagonism Abolished the Anti-seizure Effects of Exogenous Ketone Supplementation in Wistar Albino Glaxo Rijswijk Rats.

Authors:  Zsolt Kovács; Dominic P D'Agostino; Arpád Dobolyi; Csilla Ari
Journal:  Front Mol Neurosci       Date:  2017-07-25       Impact factor: 5.639

5.  Anxiolytic Effect of Exogenous Ketone Supplementation Is Abolished by Adenosine A1 Receptor Inhibition in Wistar Albino Glaxo/Rijswijk Rats.

Authors:  Zsolt Kovács; Dominic P D'Agostino; Csilla Ari
Journal:  Front Behav Neurosci       Date:  2018-02-22       Impact factor: 3.558

6.  Inhibition of adenosine A1 receptors abolished the nutritional ketosis-evoked delay in the onset of isoflurane-induced anesthesia in Wistar Albino Glaxo Rijswijk rats.

Authors:  Zsolt Kovács; Brigitta Brunner; Dominic P D'Agostino; Csilla Ari
Journal:  BMC Anesthesiol       Date:  2020-01-30       Impact factor: 2.217

7.  Enhancement of Ketone Supplements-Evoked Effect on Absence Epileptic Activity by Co-Administration of Uridine in Wistar Albino Glaxo Rijswijk Rats.

Authors:  Brigitta Brunner; Enikő Rauch; Csilla Ari; Dominic P D'Agostino; Zsolt Kovács
Journal:  Nutrients       Date:  2021-01-15       Impact factor: 5.717

8.  Adenosine Receptors Modulate the Exogenous Ketogenic Supplement-Evoked Alleviating Effect on Lipopolysaccharide-Generated Increase in Absence Epileptic Activity in WAG/Rij Rats.

Authors:  Brigitta Brunner; Csilla Ari; Dominic P D'Agostino; Zsolt Kovács
Journal:  Nutrients       Date:  2021-11-15       Impact factor: 5.717

9.  Effects of thymoquinone, the major constituent of Nigella sativa seeds, on penicillin-induced epileptiform activity in rats.

Authors:  Ersin Beyazcicek; Seyit Ankarali; Ozge Beyazcicek; Handan Ankarali; Serif Demir; Recep Ozmerdivenli
Journal:  Neurosciences (Riyadh)       Date:  2016-04       Impact factor: 0.906

10.  Potentiation of pentylenetetrazole-induced neuronal damage by dimethyl sulfoxide in chemical kindling model in rats.

Authors:  Puja Kumari; Neha Singh; Lekha Saha
Journal:  Indian J Pharmacol       Date:  2018 Mar-Apr       Impact factor: 1.200
  10 in total

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