| Literature DB >> 21319754 |
Yael Levi-Kalisman1, Pablo D Jadzinsky, Nir Kalisman, Hironori Tsunoyama, Tatsuya Tsukuda, David A Bushnell, Roger D Kornberg.
Abstract
The synthesis of Au(102)(p-MBA)(44) nanoparticles on a preparative scale in high yield is described. Various analytical methods are shown to give results consistent with the composition and known structure of the particles, showing the preparation is essentially homogeneous, and attesting to the validity of the methods as well. Derivatization of the particles with proteins and DNA is demonstrated, and conditions are described for imaging individual particles by cryo-EM at low electron dose, close to focus, conditions optimal for recording high-resolution details.Entities:
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Year: 2011 PMID： 21319754 DOI： 10.1021/ja109131w
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419