Literature DB >> 21318758

Lyophilization of nonviral gene delivery systems.

S D Allison1, T J Anchordoquy.   

Abstract

This chapter presents a qualitative description of the freeze-drying process as it pertains to the development of stable, dry polycation-DNA complex formulations. It is not intended to be a comprehensive treatise on freeze-drying. Readers are referred to a series of excellent papers by Pikal (1-5) for more detailed, quantitative explanations of the freeze-drying process.

Year:  2001        PMID: 21318758     DOI: 10.1385/1-59259-139-6:225

Source DB:  PubMed          Journal:  Methods Mol Med        ISSN: 1543-1894


  2 in total

1.  Development of a Parenteral Formulation of NTS-Polyplex Nanoparticles for Clinical Purpose.

Authors:  María E Aranda-Barradas; Maripaz Márquez; Liliana Quintanar; Jaime Santoyo-Salazar; Armando J Espadas-Álvarez; Daniel Martínez-Fong; Elizabeth García-García
Journal:  Pharmaceutics       Date:  2018-01-03       Impact factor: 6.321

2.  Effects of lyoprotectants on long-term stability and transfection efficacy of lyophilized poly(lactide-co-glycolide)-graft-polyethylenimine/plasmid DNA polyplexes.

Authors:  Joshua Woo; Jeoung Soo Lee
Journal:  Nanomedicine (Lond)       Date:  2021-05-28       Impact factor: 5.307

  2 in total

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