Literature DB >> 21317939

Biological functions of microRNAs.

Yong Huang1, Xing Jia Shen, Quan Zou, Qiao Ling Zhao.   

Abstract

The small regulatory non-coding RNA molecules, known as microRNAs (miRNAs), have been recognized as potential regulator of gene expression and modulate the gene function at the post-transcriptional level. It is now clear that miRNA biogenesis and function are related to the molecular mechanisms of various clinical diseases, which can potentially regulate every aspect of cellular activity, including differentiation and development, metabolism, proliferation, apoptotic cell death viral infection and tumorgenesis. Here, we review recent work and provide insight into the diverse roles of miRNAs.

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Year:  2010        PMID: 21317939     DOI: 10.1134/s1068162010060026

Source DB:  PubMed          Journal:  Bioorg Khim        ISSN: 0132-3423


  16 in total

1.  Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b.

Authors:  Konstantina Kyritsi; Fanyin Meng; Tianhao Zhou; Nan Wu; Julie Venter; Heather Francis; Lindsey Kennedy; Paolo Onori; Antonio Franchitto; Francesca Bernuzzi; Pietro Invernizzi; Kelly McDaniel; Romina Mancinelli; Domenico Alvaro; Eugenio Gaudio; Gianfranco Alpini; Shannon Glaser
Journal:  Am J Pathol       Date:  2017-05-12       Impact factor: 4.307

2.  MicroRNA-93 Downregulation Ameliorates Cerebral Ischemic Injury Through the Nrf2/HO-1 Defense Pathway.

Authors:  Peng Wang; Xinyu Liang; Yijun Lu; Xingjian Zhao; Jia Liang
Journal:  Neurochem Res       Date:  2016-06-14       Impact factor: 3.996

3.  Down-regulation of miRNA-30a alleviates cerebral ischemic injury through enhancing beclin 1-mediated autophagy.

Authors:  Peng Wang; Jia Liang; Yun Li; Jiefei Li; Xuan Yang; Xinxin Zhang; Song Han; Shujuan Li; Junfa Li
Journal:  Neurochem Res       Date:  2014-04-26       Impact factor: 3.996

4.  Upregulation of microRNA-203 is associated with advanced tumor progression and poor prognosis in epithelial ovarian cancer.

Authors:  Shaosheng Wang; Xiaohong Zhao; Jie Wang; Yingmei Wen; Linjing Zhang; Dezhu Wang; Huili Chen; Qiuxia Chen; Wei Xiang
Journal:  Med Oncol       Date:  2013-08-07       Impact factor: 3.064

5.  MicroRNAs in Neurotoxicity.

Authors:  Prameet Kaur; Arunmozhiarasi Armugam; Kandiah Jeyaseelan
Journal:  J Toxicol       Date:  2012-03-06

6.  Prognostic implications of microRNA-100 and its functional roles in human epithelial ovarian cancer.

Authors:  Dong-Xian Peng; Min Luo; Li-Wen Qiu; Yuan-Li He; Xue-Feng Wang
Journal:  Oncol Rep       Date:  2012-01-11       Impact factor: 3.906

7.  Ionizing radiation-induced microRNA expression changes in cultured RGC-5 cells.

Authors:  Kaijun Wang; Meijuan Zhu; Panpan Ye; Guodi Chen; Wei Wang; Min Chen
Journal:  Mol Med Rep       Date:  2015-06-16       Impact factor: 2.952

8.  Diversity and functional convergence of small noncoding RNAs in male germ cell differentiation and fertilization.

Authors:  Jesús García-López; Lola Alonso; David B Cárdenas; Haydeé Artaza-Alvarez; Juan de Dios Hourcade; Sergio Martínez; Miguel A Brieño-Enríquez; Jesús Del Mazo
Journal:  RNA       Date:  2015-03-24       Impact factor: 4.942

9.  TLR4/NF-κB-responsive microRNAs and their potential target genes: a mouse model of skeletal muscle ischemia-reperfusion injury.

Authors:  Johnson Chia-Shen Yang; Shao-Chun Wu; Cheng-Shyuan Rau; Yi-Chun Chen; Tsu-Hsiang Lu; Yi-Chan Wu; Siou-Ling Tzeng; Chia-Jung Wu; Ching-Hua Hsieh
Journal:  Biomed Res Int       Date:  2015-01-26       Impact factor: 3.411

10.  A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer.

Authors:  Lin Wang; Miao-Jun Zhu; Ai-Min Ren; Hong-Fei Wu; Wu-Mei Han; Ruo-Ying Tan; Rui-Qin Tu
Journal:  PLoS One       Date:  2014-05-09       Impact factor: 3.240

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