Literature DB >> 21316784

The effect of local breast radiotherapy on circulating CD34(+) cells.

Nehad M Alajez1, Wei Wang, Debashis Biswas, Amy Teh, Robert Sutherland, Melania Pintilie, Mark Minden, Hans Messner, Anthony Fyles, Mary Gospodarowicz, Armand Keating, Fei-Fei Liu.   

Abstract

The number of circulating CD34(+) (hematopoietic stem) cells (HSCs) was observed to decline by 15% in breast cancer patients after starting adjuvant radiation therapy, regardless of age or preceding chemotherapy. These data demonstrate that local radiation therapy can profoundly affect HSC homeostasis, which might have a myriad of important implications.
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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Year:  2011        PMID: 21316784     DOI: 10.1016/j.radonc.2011.01.003

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  1 in total

1.  Inflammatory Biomarkers, Hematopoietic Stem Cells, and Symptoms in Breast Cancer Patients Undergoing Adjuvant Radiation Therapy.

Authors:  Wei Shi; Shagun Misra; Madeline Li; Jie Su; Lisa P Chong; Megan McCuske; Justin Williams; Wei Xu; Laleh S Ghoraie; D Robert Sutherland; Kathy Han; Mark D Minden; Scott V Bratman; Kenneth W Yip; Fei-Fei Liu
Journal:  JNCI Cancer Spectr       Date:  2020-05-08
  1 in total

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