Literature DB >> 21316427

Phytochemical potential of Eruca sativa for inhibition of melanoma tumor growth.

M Khoobchandani1, N Ganesh, S Gabbanini, L Valgimigli, M M Srivastava.   

Abstract

Solvent extracts from the aerial and root parts and seed oil from E. sativa (rocket salad) were assayed for anticancer activity against melanoma cells. The seed oil (isothiocyanates rich) significantly (p<0.01) reduced the tumor growth comparable to the control. Remarkably, the seed oil inhibited melanoma growth and angiogenesis in mice without any major toxicity. The findings qualify seed oil for further investigations in the real of cancer prevention and treatment.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID: 21316427     DOI: 10.1016/j.fitote.2011.02.004

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  11 in total

1.  Antimelanoma Potential of Eruca sativa Seed Oil and its Bioactive Principles.

Authors:  Prachi Bansal; S Medhe; N Ganesh; M M Srivastava
Journal:  Indian J Pharm Sci       Date:  2015 Mar-Apr       Impact factor: 0.975

Review 2.  Food Processing and the Mediterranean Diet.

Authors:  Richard Hoffman; Mariette Gerber
Journal:  Nutrients       Date:  2015-09-17       Impact factor: 5.717

Review 3.  Nitrates and glucosinolates as strong determinants of the nutritional quality in rocket leafy salads.

Authors:  Marina Cavaiuolo; Antonio Ferrante
Journal:  Nutrients       Date:  2014-04-14       Impact factor: 5.717

4.  Eruca sativa seed extract: A novel natural product able to counteract neuroinflammation.

Authors:  Agnese Gugliandolo; Sabrina Giacoppo; Marcello Ficicchia; Angelo Aliquò; Placido Bramanti; Emanuela Mazzon
Journal:  Mol Med Rep       Date:  2018-03-07       Impact factor: 2.952

5.  The fatty acid-rich fraction of Eruca sativa (rocket salad) leaf extract exerts antidiabetic effects in cultured skeletal muscle, adipocytes and liver cells.

Authors:  Mona H Hetta; Asmaa I Owis; Pierre S Haddad; Hoda M Eid
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

6.  Synthesis and characterisation of metal nanoparticles and their effects on seed germination and seedling growth in commercially important Eruca sativa.

Authors:  Mehreen Zaka; Bilal Haider Abbasi; Latif-Ur Rahman; Afzal Shah; Muhammad Zia
Journal:  IET Nanobiotechnol       Date:  2016-06       Impact factor: 1.847

7.  The Cytotoxicity of Dacarbazine Potentiated by Sea Cucumber Saponin in Resistant B16F10 Melanoma Cells through Apoptosis Induction.

Authors:  Javad Baharara; Elaheh Amini; Najme Nikdel; Farzaneh Salek-Abdollahi
Journal:  Avicenna J Med Biotechnol       Date:  2016 Jul-Sep

Review 8.  Applicability of Plant Extracts in Preclinical Studies of Melanoma: A Systematic Review.

Authors:  Kamylla Rafaella Sena Albuquerque; Nívea Maria Pacheco; Thalia Del Rosario Loyo Casao; Fabiana Cristina Silveira Alves de Melo; Rômulo Dias Novaes; Reggiani Vilela Gonçalves
Journal:  Mediators Inflamm       Date:  2018-07-26       Impact factor: 4.711

9.  Effect of Plasma Activated Water on Selected Chemical Compounds of Rocket-Salad (Eruca sativa Mill.) Leaves.

Authors:  Doaa Abouelenein; Simone Angeloni; Giovanni Caprioli; Jessica Genovese; Ahmed M Mustafa; Franks Kamgang Nzekoue; Riccardo Petrelli; Pietro Rocculi; Gianni Sagratini; Silvia Tappi; Elisabetta Torregiani; Sauro Vittori
Journal:  Molecules       Date:  2021-12-20       Impact factor: 4.411

10.  Quantifying Temperature and Osmotic Stress Impact on Seed Germination Rate and Seedling Growth of Eruca sativa Mill. via Hydrothermal Time Model.

Authors:  Sheharyar Khan; Abd Ullah; Sami Ullah; Muhammad Hamzah Saleem; Mohammad K Okla; Abdulrahman Al-Hashimi; Yinglong Chen; Shafaqat Ali
Journal:  Life (Basel)       Date:  2022-03-09
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