Literature DB >> 21314739

Myeloid-derived suppressor cells: a double-edged sword?

Agnieszka Pastuła1, Janusz Marcinkiewicz.   

Abstract

Myeloid-derived suppressor cells are important cell population with an immunoregulatory potential in both adaptive and innate immunity. Their immunosuppressive activity is widely accepted. However, emerging evidence suggests that this heterogeneous cell population can be, under some circumstances, immunostimulatory rather than suppressive. This finding can shed a new light on antitumour immunity which is believed to be impaired in immunosuppressive environments.
© 2011 The Authors. International Journal of Experimental Pathology © 2011 International Journal of Experimental Pathology.

Mesh：

Year:  2011        PMID： 21314739      PMCID： PMC3081509          DOI： 10.1111/j.1365-2613.2010.00754.x

Source DB:  PubMed          Journal:  Int J Exp Pathol        ISSN： 0959-9673            Impact factor:   1.925


  59 in total

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  14 in total

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