Literature DB >> 21314468

Unexpected severe hepatotoxicity of ciprofloxacine: two case reports.

Cabir Alan1, Hasan Koçoğlu, Ahmet Reşit Ersay, Yunus Ertung, Hasan Anıl Kurt.   

Abstract

Ciprofloxacin is a fluoroquinolone antibiotic that has a relatively low rate of occurence of adverse side effects. However, increasing evidences suggest that ciprofloxacin may cause unexpected severe liver damage. Especially, the risk of hepatotoxicity is significantly higher in elderly men receiving drug for a long time. In this article, 2 cases of unexpected severe hepatoxicity of ciprofloxacin are presented.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21314468     DOI： 10.3109/01480545.2010.495392

Source DB:  PubMed          Journal:  Drug Chem Toxicol        ISSN： 0148-0545            Impact factor:   3.356


  3 in total

1.  The ciprofloxacin target AUC : MIC ratio is not reached in hospitalized patients with the recommended dosing regimens.

Authors:  Michiel Haeseker; Leo Stolk; Fred Nieman; Christian Hoebe; Cees Neef; Cathrien Bruggeman; Annelies Verbon
Journal:  Br J Clin Pharmacol       Date:  2013-01       Impact factor: 4.335

Review 2.  Fluoroquinolone-induced liver injury: three new cases and a review of the literature.

Authors:  Anna Licata; Claudia Randazzo; Ilaria Morreale; Giuseppe Butera; Natale D'Alessandro; Antonio Craxì
Journal:  Eur J Clin Pharmacol       Date:  2012-01-14       Impact factor: 3.064

Review 3.  Idiosyncratic Drug-Induced Liver Injury Due to Ciprofloxacin: A Report of Two Cases and Review of the Literature.

Authors:  Milan Radovanovic; Tetyana Dushenkovska; Ivan Cvorovic; Natasa Radovanovic; Vimala Ramasamy; Katarina Milosavljevic; Jelena Surla; Mladen Jecmenica; Miroslav Radulovic; Tamara Milovanovic; Igor Dumic
Journal:  Am J Case Rep       Date:  2018-09-29
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.