BACKGROUND: Health-related quality of life has recently been suggested as a supplement to the traditional neurological outcome measures from the patient's perspective according to the World Health Organization model and may capture the effects of other factors such as posttraumatic stress disorder and neuroendocrine dysfunction. OBJECTIVE: To explore the profile and clinical factors of quality of life after aneurysmal subarachnoid hemorrhage using the data we obtained from the recently completed Intravenous Magnesium Sulphate After Aneurysmal Subarachnoid Hemorrhage (IMASH) trial. METHODS: This study was registered at www.strokecenter.org/trials and www.ClinicalTrials.gov (NCT00124150). Data from a patient cohort obtained with the Short Form-36 questionnaire completed at 6 months were used for analysis. RESULTS: Patients with aneurysmal subarachnoid hemorrhage demonstrated a decrease in quality of life according to the Short Form-36 at 6 months. The physical and mental health scores correlated with the Extended Glasgow Outcome Scale and had the potential to avoid the ceiling effect. Multiple regression analyses showed that the physical component scores were related to age, World Federation of Neurological Surgeons grade, and chronic hydrocephalus and that the mental component scores were not related to the traditional prognostic factors. CONCLUSION: Subarachnoid hemorrhage caused a decrease in quality of life. Chronic hydrocephalus is related to a decrease in physical health quality of life.
BACKGROUND: Health-related quality of life has recently been suggested as a supplement to the traditional neurological outcome measures from the patient's perspective according to the World Health Organization model and may capture the effects of other factors such as posttraumatic stress disorder and neuroendocrine dysfunction. OBJECTIVE: To explore the profile and clinical factors of quality of life after aneurysmal subarachnoid hemorrhage using the data we obtained from the recently completed Intravenous Magnesium Sulphate After Aneurysmal Subarachnoid Hemorrhage (IMASH) trial. METHODS: This study was registered at www.strokecenter.org/trials and www.ClinicalTrials.gov (NCT00124150). Data from a patient cohort obtained with the Short Form-36 questionnaire completed at 6 months were used for analysis. RESULTS:Patients with aneurysmal subarachnoid hemorrhage demonstrated a decrease in quality of life according to the Short Form-36 at 6 months. The physical and mental health scores correlated with the Extended Glasgow Outcome Scale and had the potential to avoid the ceiling effect. Multiple regression analyses showed that the physical component scores were related to age, World Federation of Neurological Surgeons grade, and chronic hydrocephalus and that the mental component scores were not related to the traditional prognostic factors. CONCLUSION:Subarachnoid hemorrhage caused a decrease in quality of life. Chronic hydrocephalus is related to a decrease in physical health quality of life.
Authors: Gang Lu; Man Sze Wong; Mark Zhi Qiang Xiong; Chi Kwan Leung; Xian Wei Su; Jing Ye Zhou; Wai Sang Poon; Vera Zhi Yuan Zheng; Wai Yee Chan; George Kwok Chu Wong Journal: J Am Heart Assoc Date: 2017-04-25 Impact factor: 5.501
Authors: Alexander Hammer; Frank Erbguth; Matthias Hohenhaus; Christian M Hammer; Hannes Lücking; Markus Gesslein; Monika Killer-Oberpfalzer; Hans-Herbert Steiner; Hendrik Janssen Journal: BMC Neurol Date: 2021-01-19 Impact factor: 2.474
Authors: Giuseppe E Umana; S Ottavio Tomasi; Paolo Palmisciano; Gianluca Scalia; Valerio Da Ros; Rahman Al-Schameri; Stefano M Priola; Lara Brunasso; Giuseppe Roberto Giammalva; Federica Paolini; Roberta Costanzo; Lapo Bonosi; Rosa Maria Gerardi; Rosario Maugeri; Lidia Strigari; Philip E Stieg; Giuseppe Esposito; Michael T Lawton; Christoph J Griessenauer; Peter A Winkler Journal: Front Surg Date: 2022-04-05
Authors: Xian Wei Su; Anna Ho Yin Chan; Gang Lu; Marie Lin; Johnny Sze; Jing Ye Zhou; Wai Sang Poon; Qiang Liu; Vera Zhi Yuan Zheng; George Kwok Chu Wong Journal: PLoS One Date: 2015-12-16 Impact factor: 3.240