PURPOSE OF REVIEW: The purpose of this review is to describe important findings published during the past 18 months using bronchoalveolar lavage (BAL) for diagnosis of pulmonary mycoses. RECENT FINDINGS: Clinical studies and meta-analysis have established a high sensitivity and specificity for Aspergillus galactomannan testing of BAL specimens for diagnosis of invasive aspergillosis, superior to that observed with other diagnostic methods. Similar findings have been reported in histoplasmosis and blastomycosis. SUMMARY: Fungal antigen testing of BAL specimens is recommended if bronchoscopy is performed for diagnosis of pulmonary infiltrates in patient groups at risk for aspergillosis or the endemic mycoses if the diagnosis cannot be established by evaluation of sputum specimens or detection of antigen in the urine or serum.
PURPOSE OF REVIEW: The purpose of this review is to describe important findings published during the past 18 months using bronchoalveolar lavage (BAL) for diagnosis of pulmonary mycoses. RECENT FINDINGS: Clinical studies and meta-analysis have established a high sensitivity and specificity for Aspergillus galactomannan testing of BAL specimens for diagnosis of invasive aspergillosis, superior to that observed with other diagnostic methods. Similar findings have been reported in histoplasmosis and blastomycosis. SUMMARY: Fungal antigen testing of BAL specimens is recommended if bronchoscopy is performed for diagnosis of pulmonary infiltrates in patient groups at risk for aspergillosis or the endemic mycoses if the diagnosis cannot be established by evaluation of sputum specimens or detection of antigen in the urine or serum.
Authors: Peter Pongratz; Hermann Laferl; Günther Strau; Gerold Stanek; Christoph Wenisch Journal: Wien Klin Wochenschr Date: 2012-10-26 Impact factor: 1.704
Authors: Mojtaba Taghizadeh-Armaki; Mohammad T Hedayati; Vahid Moqarabzadeh; Saham Ansari; Saeed Mahdavi Omran; Hossein Zarrinfar; Sasan Saber; Paul E Verweij; David W Denning; Seyedmojtaba Seyedmousavi Journal: J Med Microbiol Date: 2017-07-12 Impact factor: 2.472
Authors: Cornelia Lass-Flörl; Wolfgang Mutschlechner; Maria Aigner; Katharina Grif; Claudia Marth; Michael Girschikofsky; Wilhelm Grander; Richard Greil; Gudrun Russ; Peter Cerkl; Mirjam Eller; Gabriele Kropshofer; Stephan Eschertzhuber; Hermann Kathrein; Stefan Schmid; Ronny Beer; Ingo Lorenz; Igor Theurl; David Nachbaur Journal: J Clin Microbiol Date: 2012-12-26 Impact factor: 5.948
Authors: J Knapp; G Marx; K Weismüller; S Steinebach; C Lichtenstern; E Popp; K Mayer; F M Brunkhorst; M A Weigand; M Bernhard Journal: Anaesthesist Date: 2011-11 Impact factor: 1.041