| Literature DB >> 21309519 |
Takumi Higashi1, Yoichiro Isobe, Hitoshi Ouchi, Hiroto Suzuki, Yuko Okazaki, Tomohiro Asakawa, Takumi Furuta, Toshiyuki Wakimoto, Toshiyuki Kan.
Abstract
The efficient total syntheses of (+)-methoxyphenylkainic acid (3) and (+)-phenylkainic acid (4) were achieved using a rhodium carbenoid-mediated intermolecular C-H insertion reaction. Complete stereoselective construction of the kainoid skeleton was accomplished by utilizing the stereochemistry at the C-4 position as a pivotal stereogenic center.Entities:
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Year: 2011 PMID： 21309519 DOI： 10.1021/ol103131p
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005