Literature DB >> 21308200

[Neurocysticercosis diagnosis and management in Peru].

Herbert Saavedra1, Isidro Gonzales, Manuel A Alvarado, Miguel A Porras, Victor Vargas, Román A Cjuno, Hector H Garcia, S Manuel Martinez.   

Abstract

Neurocysticercosis (NCC) is the most common parasitic disease of the central nervous system and is caused by larvae of the tapeworm Taenia solium. NCC is endemic in almost all developing countries. It presents as intraparenchymal forms associated with seizures or as extraparenchymal forms associated with intracranial hypertension. The clinical and epidemiological suspicion are important but the diagnosis is made primarily by images and confirmed by serology. Computed tomography (CT) and magnetic resonance imaging tests are used. Immunodiagnosis by Western Blot, which is currently perform in the Instituto Nacional de Ciencias Neurológicas in serum and cerebrospinal fluid serves as confirmatory test. Treatment involves symptomatic measures (control of seizures or intracranial hypertension) and anticysticercal medications (albendazole and praziquantel). Anticysticercal treatment should be used under hospital conditions because of secondary effects.

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Year:  2010        PMID: 21308200     DOI: 10.1590/s1726-46342010000400015

Source DB:  PubMed          Journal:  Rev Peru Med Exp Salud Publica        ISSN: 1726-4634


  3 in total

1.  A dot-ELISA using a partially purified cathepsin-L-like protein fraction from Taenia solium cysticerci, for the diagnosis of human neurocysticercosis.

Authors:  R Piña; A H Gutiérrez; R H Gilman; D Rueda; C Sifuentes; M Flores; P Sheen; S Rodriguez; H H García; M Zimic
Journal:  Ann Trop Med Parasitol       Date:  2011-06

2.  TsAg5, a Taenia solium cysticercus protein with a marginal trypsin-like activity in the diagnosis of human neurocysticercosis.

Authors:  Analiz Rueda; Cecilia Sifuentes; Robert H Gilman; Andrés H Gutiérrez; Ruby Piña; Nancy Chile; Sebastián Carrasco; Sandra Larson; Holger Mayta; Manuela Verástegui; Silvia Rodriguez; Marcel Gutiérrez-Correa; Héctor H García; Patricia Sheen; Mirko Zimic
Journal:  Mol Biochem Parasitol       Date:  2011-08-26       Impact factor: 1.759

3.  Neurocysticercosis as a cause of epilepsy and seizures in two community-based studies in a cysticercosis-endemic region in Peru.

Authors:  Luz M Moyano; Mayuko Saito; Silvia M Montano; Guillermo Gonzalvez; Sandra Olaya; Viterbo Ayvar; Isidro González; Luis Larrauri; Victor C W Tsang; Fernando Llanos; Silvia Rodríguez; Armando E Gonzalez; Robert H Gilman; Hector H Garcia
Journal:  PLoS Negl Trop Dis       Date:  2014-02-13
  3 in total

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