Literature DB >> 21305562

The Oculobulbar Facial Respiratory score is a tool to assess bulbar function in myasthenia gravis patients.

Maria E Farrugia1, Heather D Harle, Caroline Carmichael, Ted M Burns.   

Abstract

The Oculobulbar Facial Respiratory (OBFR) score is a tool that objectively measures bulbar function in myasthenia gravis (MG). In this study, we analyzed the relation between the OBFR and the MG Activities of Daily Living (MG-ADL) score, and also with the more recently described MG Composite and 15-item MG Quality-of-Life (MG-QOL15) scales. We recruited 42 patients from two centers and assessed them on two occasions, approximately 6 months apart, using the OBFR, MG Composite, MG-ADL, and MG-QOL15 scales. The 'modified' OBFR score was derived from the original OBFR score. The OBFR score correlated significantly with the MG Composite, MG-ADL, and MG-QOL15 scores for both assessments, and with the sum of the bulbar items for all three scores. It also correlated strongly with the individual bulbar-related items of all three scores. The 'modified' OBFR score also correlated significantly with all the aforementioned scores. This study confirmed construct validity of the OBFR and 'modified' OBFR scores.
Copyright © 2010 Wiley Periodicals, Inc.

Entities:  

Mesh:

Year:  2011        PMID: 21305562     DOI: 10.1002/mus.21880

Source DB:  PubMed          Journal:  Muscle Nerve        ISSN: 0148-639X            Impact factor:   3.217


  3 in total

1.  Seropositivity for NT5c1A antibody in sporadic inclusion body myositis predicts more severe motor, bulbar and respiratory involvement.

Authors:  N A Goyal; T M Cash; U Alam; S Enam; P Tierney; N Araujo; F H Mozaffar; A Pestronk; T Mozaffar
Journal:  J Neurol Neurosurg Psychiatry       Date:  2015-04-09       Impact factor: 10.154

Review 2.  The health-related quality of life, mental health and mental illnesses of patients with inclusion body myositis (IBM): results of a mixed methods systematic review.

Authors:  Katja C Senn; Laura Gumbert; Simone Thiele; Sabine Krause; Maggie C Walter; Klaus H Nagels
Journal:  Orphanet J Rare Dis       Date:  2022-06-16       Impact factor: 4.303

Review 3.  Utilization of MG-ADL in myasthenia gravis clinical research and care.

Authors:  Srikanth Muppidi; Nicholas J Silvestri; Robin Tan; Kimberly Riggs; Trevor Leighton; Glenn A Phillips
Journal:  Muscle Nerve       Date:  2022-01-06       Impact factor: 3.852

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.